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Anti-LGALS3BP Polyclonal Antibody 是一种 Rabbit 抗体,靶向 LGALS3BP。Anti-LGALS3BP Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF,ELISA。
Anti-LGALS3BP Polyclonal Antibody 是一种 Rabbit 抗体,靶向 LGALS3BP。Anti-LGALS3BP Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF,ELISA。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,175 | 5日内发货 | |
| 100 μL | ¥ 1,975 | 5日内发货 |
| 产品描述 | Anti-LGALS3BP Polyclonal Antibody is a Rabbit antibody targeting LGALS3BP. Anti-LGALS3BP Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF,ELISA. |
| Ig Type | IgG |
| 反应种属 | Human,Mouse |
| 应用 | WBIHC-PIHC-FrIFELISA |
| 推荐剂量 | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; ELISA: 1:5000-10000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Secreted. Secreted, extracellular space, extracellular matrix. |
| 组织特异性 | Ubiquitous. Detected in body fluids such as semen, milk, serum, tears, saliva and urine. Expressed by keratinocytes and fibroblasts. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | LGALS3BP is a ligand of galectin 3, and has been suggested to influence tumor proliferation and metastasis formation. Galectins and their ligands have been implicated in cell transformation and cancer metastasis, and found to have prognostic value. LGALS3BP also known as Mac 2 BP,and as 90K, is a highly glycosylated, secreted protein extensively studied in human cancer, which binds galectin 1, galectin 3 and galectin 7. High expression levels of this molecule are associated with a shorter survival, the occurrence of metastasis or a reduced response to chemotherapy in patients with different types of malignancy. The mechanisms underlying the prognostic significance of 90K and galectins in cancer are far from being understood, although they may be related to the ability of these proteins to interact and, to some extent, modulate cell cell and cell matrix adhesion and apoptosis. |
| 免疫原 | KLH conjugated synthetic peptide: human LGALS3BP |
| 抗原种属 | Human |
| 基因名称 | LGALS3BP |
| 基因ID | |
| 蛋白名称 | Galectin-3-binding protein |
| Uniprot ID | |
| 功能 | Promotes intergrin-mediated cell adhesion. May stimulate host defense against viruses and tumor cells. |
| 分子量 | Theoretical: 63 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |