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Anti-LGALS3BP Polyclonal Antibody

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货号 TMAB-08286

Anti-LGALS3BP Polyclonal Antibody 是一种 Rabbit 抗体,靶向 LGALS3BP。Anti-LGALS3BP Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF,ELISA。

Anti-LGALS3BP Polyclonal Antibody

Anti-LGALS3BP Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-08286

Anti-LGALS3BP Polyclonal Antibody 是一种 Rabbit 抗体,靶向 LGALS3BP。Anti-LGALS3BP Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF,ELISA。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,975
5日内发货
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产品介绍


生物活性
产品描述
Anti-LGALS3BP Polyclonal Antibody is a Rabbit antibody targeting LGALS3BP. Anti-LGALS3BP Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF,ELISA.
Ig Type
IgG
反应种属
Human,Mouse
应用WBIHC-PIHC-FrIFELISA
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; ELISA: 1:5000-10000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Secreted. Secreted, extracellular space, extracellular matrix.
组织特异性Ubiquitous. Detected in body fluids such as semen, milk, serum, tears, saliva and urine. Expressed by keratinocytes and fibroblasts.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景LGALS3BP is a ligand of galectin 3, and has been suggested to influence tumor proliferation and metastasis formation. Galectins and their ligands have been implicated in cell transformation and cancer metastasis, and found to have prognostic value. LGALS3BP also known as Mac 2 BP,and as 90K, is a highly glycosylated, secreted protein extensively studied in human cancer, which binds galectin 1, galectin 3 and galectin 7. High expression levels of this molecule are associated with a shorter survival, the occurrence of metastasis or a reduced response to chemotherapy in patients with different types of malignancy. The mechanisms underlying the prognostic significance of 90K and galectins in cancer are far from being understood, although they may be related to the ability of these proteins to interact and, to some extent, modulate cell cell and cell matrix adhesion and apoptosis.
抗原信息
免疫原
KLH conjugated synthetic peptide: human LGALS3BP
抗原种属
Human
基因名称
LGALS3BP
基因ID
蛋白名称
Galectin-3-binding protein
Uniprot ID
功能
Promotes intergrin-mediated cell adhesion. May stimulate host defense against viruses and tumor cells.
化学信息
分子量Theoretical: 63 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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