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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-LRP2 Antibody (2U476)

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货号 TMAB-08400

Anti-LRP2 Antibody (2U476) 是一种 Rabbit 抗体，靶向 LRP2。Anti-LRP2 Antibody (2U476) 可用于 IHC-P,WB,IF,IHC-Fr,ICC/IF。

Anti-LRP2 Antibody (2U476)
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Anti-LRP2 Antibody (2U476)

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Rating icon 还可以
货号 TMAB-08400

Anti-LRP2 Antibody (2U476) 是一种 Rabbit 抗体，靶向 LRP2。Anti-LRP2 Antibody (2U476) 可用于 IHC-P,WB,IF,IHC-Fr,ICC/IF。

规格价格库存数量
200 μg
¥ 5,595
5日内发货
25 μL
¥ 780
5日内发货
50 μL
¥ 1,385
5日内发货
100 μL
¥ 2,495
5日内发货
200 μL
¥ 3,995
5日内发货
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产品介绍

生物活性
产品描述
Anti-LRP2 Antibody (2U476) is a Rabbit antibody targeting LRP2. Anti-LRP2 Antibody (2U476) can be used in IHC-P,WB,IF,IHC-Fr,ICC/IF.
Ig Type
IgG
克隆号
2U476
反应种属
Mouse,Rat,Human
应用IHC-PWBIFIHC-FrICC/IF
推荐剂量
IHC-P: 1:100-500; WB: 1:500-2000; IF: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Membrane; Single-pass type I membrane protein. Membrane, coated pit.
组织特异性Absorptive epithelia, including renal proximal tubules.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The protein encoded by this gene, low density lipoprotein-related protein 2 (LRP2) or megalin, is a multi-ligand endocytic receptor that is expressed in many different tissues but primarily in absorptive epithilial tissues such as the kidney. This glycoprotein has a large amino-terminal extracellular domain, a single transmembrane domain, and a short carboxy-terminal cytoplasmic tail. The extracellular ligand-binding-domains bind diverse macromolecules including albumin, apolipoproteins B and E, and lipoprotein lipase. The LRP2 protein is critical for the reuptake of numerous ligands, including lipoproteins, sterols, vitamin-binding proteins, and hormones. This protein also has a role in cell-signaling; extracellular ligands include parathyroid horomones and the morphogen sonic hedgehog while cytosolic ligands include MAP kinase scaffold proteins and JNK interacting proteins. Recycling of this membrane receptor is regulated by phosphorylation of its cytoplasmic domain. Mutations in this gene cause Donnai-Barrow syndrome (DBS) and facio-oculoacoustico-renal syndrome (FOAR).[provided by RefSeq, Aug 2009].
抗原信息
免疫原
Recombinant Protein: mouse LRP2 protein
抗原种属
Mouse
基因名称
LRP2
基因ID
14725
蛋白名称
Low-density lipoprotein receptor-related protein 2
Uniprot ID
A2ARV4
功能
Acts together with cubilin to mediate HDL endocytosis (By similarity). May participate in regulation of parathyroid-hormone and para-thyroid-hormone-related protein release.
化学信息
分子量Theoretical: 519 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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