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Anti-CD10 Antibody (8O420)

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Anti-CD10 Antibody (8O420)
产品编号 TMAY-01180
别名 membrane metallo-endopeptidase

Anti-CD10 Antibody (8O420) 是一种 Mouse 抗体,靶向 CD10。Anti-CD10 Antibody (8O420) 可用于 IHC-P。

Anti-CD10 Antibody (8O420)
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Anti-CD10 Antibody (8O420)

Rating icon 还可以
Anti-CD10 Antibody (8O420)
产品编号 TMAY-01180 别名 membrane metallo-endopeptidase

Anti-CD10 Antibody (8O420) 是一种 Mouse 抗体,靶向 CD10。Anti-CD10 Antibody (8O420) 可用于 IHC-P。

规格价格库存数量
100 μL
¥ 1,689
5日内发货
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产品介绍

生物活性
产品描述
Anti-CD10 Antibody (8O420) is a Mouse antibody targeting CD10. Anti-CD10 Antibody (8O420) can be used in IHC-P.
别名membrane metallo-endopeptidase
Ig Type
Mouse IgG1
克隆号
8O420
交叉反应
Human
验证活性
1. Immunochemical staining of human MME in human kidney with mouse monoclonal antibody at 1:60 dilution, formalin-fixed paraffin embedded sections.
2. Immunochemical staining of human MME in human lymphoma with mouse monoclonal antibody at 1:60 dilution, formalin-fixed paraffin embedded sections.
应用
IHC-P
推荐剂量
IHC-P: 1:30-1:100
抗体种类
Monoclonal
宿主来源Mouse
构建方式This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD10/Neprilysin/MME (rh CD10/Neprilysin/MME; TMPY-02315; NP_000893.2; Tyr52-Trp750). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alters the behavior of the cell. Some CD proteins do not take part in the cell signal process but have other functions such as cell adhesion. The cluster of differentiation 10 (CD10), also known as Neprilysin and neutral endopeptidase, is a member of the CD system. CD10 is a zinc-dependent metalloprotease enzyme that had the function to degrade some small secreted peptides such as the amyloid beta-peptide. It exists as a membrane-bound protein and has a high concentration in kidney and lung tissues. Mutations in the CD10 gene can induce the familial forms of Alzheimer's disease, providing strong evidence for the protein's association with the Alzheimer's disease process. CD10 is also associated with other biochemical processes.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Human CD10/Neprilysin/MME Protein (TMPY-02315)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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