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Anti-HCFC1R1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 HCFC1R1。Anti-HCFC1R1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。
Anti-HCFC1R1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 HCFC1R1。Anti-HCFC1R1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,175 | 5日内发货 | |
| 100 μL | ¥ 1,970 | 5日内发货 | |
| 200 μL | ¥ 2,790 | 5日内发货 |
| 产品描述 | Anti-HCFC1R1 Polyclonal Antibody is a Rabbit antibody targeting HCFC1R1. Anti-HCFC1R1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| 反应种属 | Mouse,Rat (predicted:Human,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep) |
| 应用 | IHC-PIHC-FrIF |
| 推荐剂量 | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cytoplasm. Nucleus. Shuttles between the nucleus and cytoplasm in a CRM1-dependent manner. |
| 组织特异性 | Widely expressed. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | PSTPIP1 is a 416 amino acid protein that localizes to both the cytoplasm and the cytoskeleton and contains one SH3 domain and one FCH domain. Expressed at high levels in T cells and spleen and present at lower levels in thymus, lung, placenta and small intestine, PSTPIP1 interacts with CD2AP, BDP1 and c-Abl and is involved in the regulation of the Actin cytoskeleton, possibly functioning as a scaffold protein that may promote Actin polymerization. Defects in the gene encoding PSTPIP1 are the cause of PAPA syndrome (PAPAS), an autosomal dominant disease characterized by recurring inflammatory episodes that affect skin and joint tissue. Multiple isoforms of PSTPIP1 exist due to alternative splicing events. |
| 免疫原 | KLH conjugated synthetic peptide: human HCFC1R1 |
| 抗原种属 | Human |
| 基因名称 | HCFC1R1 |
| 基因ID | |
| 蛋白名称 | Host cell factor C1 regulator 1 |
| Uniprot ID | |
| 功能 | Regulates HCFC1 activity by modulating its subcellular localization. Overexpression of HCFC1R1 leads to accumulation of HCFC1 in the cytoplasm. HCFC1R1-mediated export may provide the pool of cytoplasmic HCFC1 required for import of virion-derived VP16 into the nucleus. |
| 分子量 | Theoretical: 15 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |