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Anti-HCFC1R1 Polyclonal Antibody

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货号 TMAB-06911

Anti-HCFC1R1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 HCFC1R1。Anti-HCFC1R1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-HCFC1R1 Polyclonal Antibody

Anti-HCFC1R1 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-06911

Anti-HCFC1R1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 HCFC1R1。Anti-HCFC1R1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍


生物活性
产品描述
Anti-HCFC1R1 Polyclonal Antibody is a Rabbit antibody targeting HCFC1R1. Anti-HCFC1R1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse,Rat (predicted:Human,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Nucleus. Shuttles between the nucleus and cytoplasm in a CRM1-dependent manner.
组织特异性Widely expressed.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景PSTPIP1 is a 416 amino acid protein that localizes to both the cytoplasm and the cytoskeleton and contains one SH3 domain and one FCH domain. Expressed at high levels in T cells and spleen and present at lower levels in thymus, lung, placenta and small intestine, PSTPIP1 interacts with CD2AP, BDP1 and c-Abl and is involved in the regulation of the Actin cytoskeleton, possibly functioning as a scaffold protein that may promote Actin polymerization. Defects in the gene encoding PSTPIP1 are the cause of PAPA syndrome (PAPAS), an autosomal dominant disease characterized by recurring inflammatory episodes that affect skin and joint tissue. Multiple isoforms of PSTPIP1 exist due to alternative splicing events.
抗原信息
免疫原
KLH conjugated synthetic peptide: human HCFC1R1
抗原种属
Human
基因名称
HCFC1R1
基因ID
蛋白名称
Host cell factor C1 regulator 1
Uniprot ID
功能
Regulates HCFC1 activity by modulating its subcellular localization. Overexpression of HCFC1R1 leads to accumulation of HCFC1 in the cytoplasm. HCFC1R1-mediated export may provide the pool of cytoplasmic HCFC1 required for import of virion-derived VP16 into the nucleus.
化学信息
分子量Theoretical: 15 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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