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Anti-P2Y12 Polyclonal Antibody

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货号 TMAB-01315

别名 SP1999, SP 1999, Putative G protein coupled receptor, Purinergic receptor P2Y G protein coupled 12, Purinergic receptor P2RY12, Platelet ADP receptor, P2Y12R, P2Y12 platelet ADP receptor, P2Y12, P2Y(cyc), P2Y(ADP), P2Y(AC), P2Y(12)R, P2Y purinoceptor 12, P2Y 12, P2T(AC), P2RY12, P2RY 12, HORK3, HORK 3, Gi coupled ADP receptor HORK3, Gi coupled ADP receptor HORK 3, G protein coupled receptor SP1999, BDPLT8, ADPG-R, ADPGR, ADP-glucose receptor

Anti-P2Y12 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 P2Y12。Anti-P2Y12 Polyclonal Antibody 可用于 WB。

Anti-P2Y12 Polyclonal Antibody

Anti-P2Y12 Polyclonal Antibody

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货号 TMAB-01315 别名 SP1999, SP 1999, Putative G protein coupled receptor, Purinergic receptor P2Y G protein coupled 12, Purinergic receptor P2RY12, Platelet ADP receptor, P2Y12R, P2Y12 platelet ADP receptor, P2Y12, P2Y(cyc), P2Y(ADP), P2Y(AC), P2Y(12)R, P2Y purinoceptor 12, P2Y 12, P2T(AC), P2RY12, P2RY 12, HORK3, HORK 3, Gi coupled ADP receptor HORK3, Gi coupled ADP receptor HORK 3, G protein coupled receptor SP1999, BDPLT8, ADPG-R, ADPGR, ADP-glucose receptor

Anti-P2Y12 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 P2Y12。Anti-P2Y12 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

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产品描述
Anti-P2Y12 Polyclonal Antibody is a Rabbit antibody targeting P2Y12. Anti-P2Y12 Polyclonal Antibody can be used in WB.
别名SP1999, SP 1999, Putative G protein coupled receptor, Purinergic receptor P2Y G protein coupled 12, Purinergic receptor P2RY12, Platelet ADP receptor, P2Y12R, P2Y12 platelet ADP receptor, P2Y12, P2Y(cyc), P2Y(ADP), P2Y(AC), P2Y(12)R, P2Y purinoceptor 12, P2Y 12, P2T(AC), P2RY12, P2RY 12, HORK3, HORK 3, Gi coupled ADP receptor HORK3, Gi coupled ADP receptor HORK 3, G protein coupled receptor SP1999, BDPLT8, ADPG-R, ADPGR, ADP-glucose receptor
Ig Type
IgG
反应种属
Mouse (predicted:Human)
验证活性
Sample:
Lane 1: Cerebrum (Mouse) Lysate at 40 μg
Lane 2: Cerebellum (Mouse) Lysate at 40 μg
Primary:
Anti-P2Y12 (TMAB-01315) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 50 kDa
Observed band size: 49 kDa
verifiedActivity
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell membrane; Multi-pass membrane protein.
组织特异性Highly expressed in the platelets, lower levels in the brain. Lowest levels in the lung, appendix, pituitary and adrenal gland. Expressed in the spinal cord and in the fetal brain.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1 mg/mL
研究背景Nucleotides are emerging as important extracellular signaling molecules that mediate several effects, such as proliferation, differentiation , chemotaxis and cytokine release. The P2 receptor family is activated by the binding of nucleotides and is divided into two subfamilies, P2X and P2Y. The P2X receptor family is comprised of ligand-gated ion channels that allow for the increased permeability of calcium into the cell in response to extracellular ATP. The P2Y receptor family are G protein-coupled receptors which mediate the effects of extracellular nucleotides, primarily through the activation of phospholipase C. To some extent, the P2Y receptors can also activate potassium channels or, alternatively, inhibit adenylate cyclase and N-type calcium channels in response to extracellular nucleotides. Human platelets express two G protein-coupled nucleotide receptors, P2Y1 and P2Y12. P2Y12 is a receptor for ADP and ATP coupled to G-proteins that inhibit the adenylyl cyclase second messenger system. P2Y12 is an integral membrane protein involved in platelet aggregation. It is highly expressed in platelets, with lower levels in the brain, lung, appendix, pituitary and adrenal gland.
抗原信息
免疫原
KLH conjugated synthetic peptide: human P2Y12
抗原种属
Human
基因名称
P2RY12
基因ID
64805
蛋白名称
P2Y purinoceptor 12
Uniprot ID
Q9H244
功能
Receptor for ADP and ATP coupled to G-proteins that inhibit the adenylyl cyclase second messenger system. Not activated by UDP and UTP. Involved in platelets aggregation.
化学信息
分子量Theoretical: 39 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | store at -20°C

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