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Anti-P2Y12 Polyclonal Antibody
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产品编号 TMAB-01315
Anti-P2Y12 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 P2Y12。Anti-P2Y12 Polyclonal Antibody 可用于 WB。
Anti-P2Y12 Polyclonal Antibody
Anti-P2Y12 Polyclonal Antibody
还可以产品编号 TMAB-01315
Anti-P2Y12 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 P2Y12。Anti-P2Y12 Polyclonal Antibody 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,170 | 5日内发货 | |
| 100 μL | ¥ 1,975 | 5日内发货 | |
| 200 μL | ¥ 2,785 | 5日内发货 |
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产品介绍
生物活性
抗原信息
| 产品描述 | Anti-P2Y12 Polyclonal Antibody is a Rabbit antibody targeting P2Y12. Anti-P2Y12 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| 交叉反应 | Mouse (predicted:Human) |
| 验证活性 | Sample: Lane 1: Cerebrum (Mouse) Lysate at 40 μg Lane 2: Cerebellum (Mouse) Lysate at 40 μg Primary: Anti-P2Y12 (TMAB-01315) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 50 kDa Observed band size: 49 kDa |
| 应用 | |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cell membrane; Multi-pass membrane protein. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究背景 | Nucleotides are emerging as important extracellular signaling molecules that mediate several effects, such as proliferation, differentiation , chemotaxis and cytokine release. The P2 receptor family is activated by the binding of nucleotides and is divided into two subfamilies, P2X and P2Y. The P2X receptor family is comprised of ligand-gated ion channels that allow for the increased permeability of calcium into the cell in response to extracellular ATP. The P2Y receptor family are G protein-coupled receptors which mediate the effects of extracellular nucleotides, primarily through the activation of phospholipase C. To some extent, the P2Y receptors can also activate potassium channels or, alternatively, inhibit adenylate cyclase and N-type calcium channels in response to extracellular nucleotides. Human platelets express two G protein-coupled nucleotide receptors, P2Y1 and P2Y12. P2Y12 is a receptor for ADP and ATP coupled to G-proteins that inhibit the adenylyl cyclase second messenger system. P2Y12 is an integral membrane protein involved in platelet aggregation. It is highly expressed in platelets, with lower levels in the brain, lung, appendix, pituitary and adrenal gland. |
| 免疫原 | KLH conjugated synthetic peptide: human P2Y12 |
| 抗原种属 | Human |
| 基因ID | |
| Uniprot ID |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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