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Anti-CD64 Antibody-APC (8F637)
还可以产品编号 TMAY-03088A
Anti-CD64 Antibody-APC (8F637) 是一种 APC-conjugated Rabbit 抗体，靶向 CD64。Anti-CD64 Antibody-APC (8F637) 可用于 FCM。
Anti-CD64 Antibody-APC (8F637)
Anti-CD64 Antibody-APC (8F637)
还可以产品编号 TMAY-03088A
Anti-CD64 Antibody-APC (8F637) 是一种 APC-conjugated Rabbit 抗体，靶向 CD64。Anti-CD64 Antibody-APC (8F637) 可用于 FCM。
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产品介绍
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偶联与修饰
抗原信息
| 产品描述 | Anti-CD64 Antibody-APC (8F637) is a APC-conjugated Rabbit antibody targeting CD64. Anti-CD64 Antibody-APC (8F637) can be used in FCM. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 8F637 |
| 交叉反应 | Mouse |
| 验证活性 | Flow cytometric analysis of Mouse FCGR1(CD64) expression on Raw264.7 cells. Cells were stained with APC-conjugated anti-Mouse FCGR1(CD64). The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
| 应用 | FCM |
| 推荐剂量 | 5 μl/Test, 0.1 mg/ml |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse CD64 / FCGR1 (rM CD64 / FCGR1; TMPY-01205; NP_034316.1; Met 1-Pro 297) and conjugated with APC under optimum conditions, the unreacted APC was removed. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | PBS solution containing 0.5% BSA and 0.09% sodium azide |
| 研究背景 | High affinity immunoglobulin gamma Fc receptor I, also known as FCGR1 and CD64, is an integral membraneglycoprotein and a member of the immunoglobulin superfamily. CD64 is a high affinity receptor for the Fc region of IgG gamma and functions in both innate and adaptive immune responses. Receptors that recognize the Fc portion of IgG function in the regulation of immune response and are divided into three classes designated CD64, CD32, and CD16. CD64 is structurally composed of asignal peptidethat allows its transport to the surface of a cell, threeextracellularimmunoglobulin domainsof the C2-type that it uses to bind antibody, a hydrophobictransmembrane domain, and a short cytoplasmic tail. CD64 isconstitutivelyfound on only macrophages and monocytes, but treatment of polymorphonuclear leukocyteswith cytokines likeIFNγandG-CSFcan induce CD64 expression on these cells. The inactivation of the mouse CD64 resulted in a wide range of defects in antibody Fc-dependent functions. Mouse CD64 is an early participant in Fc-dependent cell activation and in the development of immune responses. |
| 偶联 | APC |
| 其他可选修饰符 | Unconjugated/PerCP/FITC/PE |
| 可提供抗体种类 | 5 |
| 免疫原 | Recombinant Mouse CD64 / FCGR1 protein (TMPY-01205) |
| 抗原种属 | Mouse |
| 研究领域 | Fc Receptors |
存储&运输
| 储存方式 | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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