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Anti-PTEN Polyclonal Antibody

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Anti-PTEN Polyclonal Antibody
产品编号 TMAB-01590

Anti-PTEN Polyclonal Antibody 是一种 Rabbit 抗体，靶向 PTEN。Anti-PTEN Polyclonal Antibody 可用于 WB。

Anti-PTEN Polyclonal Antibody

Anti-PTEN Polyclonal Antibody

Rating icon 还可以
Anti-PTEN Polyclonal Antibody
产品编号 TMAB-01590

Anti-PTEN Polyclonal Antibody 是一种 Rabbit 抗体，靶向 PTEN。Anti-PTEN Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-PTEN Polyclonal Antibody is a Rabbit antibody targeting PTEN. Anti-PTEN Polyclonal Antibody can be used in WB.
Ig Type
IgG
交叉反应
Mouse,Rat (predicted:Pig)
验证活性
25 μg total protein per Lane of various lysates probed with PTEN polyclonal antibody, unconjugated (TMAB-01590) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at RT for 60 min.
应用
WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Nucleus. Nucleus, PML body. Note=Monoubiquitinated form is nuclear. Nonubiquitinated form is cytoplasmic. Colocalized with PML and USP7 in PML nuclear bodies. XIAP/BIRC4 promotes its nuclear localization.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
研究背景Potential tumor suppressor. Acts as a phosphoinositide3-phosphatase by regulating PtdIns (3,4,5)P3 levels. Involved in regulation of the AKT1 signaling pathway. The unphosphorylated form cooperates with AIP1 to suppress AKT1 activation.The PTEN/MMAC1 discovers the first to have the suppress of the phosphoric acid enzyme activity cancer gene currently.The gene of PTEN locates the chromosome10q23 area, sending forth sex tumor and a few households cancers with the variety to suffer from the comprehensive disease easilyrelevant.The activity that passes to repress the Akt regulates the cell period, the cell ground rule decease and glues to connect.This text discussed PTEN structure, function and its correlationses, the PTEN is in tumor repress function mechanism.
抗原信息
免疫原
KLH conjugated synthetic peptide: human PTEN
抗原种属
Human
基因ID
5728
Uniprot ID
P60484
研究领域
Phosphatases,PTEN pathway,Phosphatases,Tumor Suppressors,Diabetes,Metabolic disorders,Obesity,Lipid Phosphatases
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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