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别名 β淀粉样蛋白片段, Beta-淀粉样蛋白片段
(Glu20)-Amyloid β-Protein (1-42) 是一种具有 Glu20 突变的淀粉样蛋白β (Aβ) 变体,该变体的原纤维化速度较慢。此突变能够减少 Aβ 的聚集倾向,进而阻止缓慢原纤化肽的累积。它是阿尔茨海默病中血管及脑内淀粉样沉积物的关键组成部分。
(Glu20)-Amyloid β-Protein (1-42) 是一种具有 Glu20 突变的淀粉样蛋白β (Aβ) 变体,该变体的原纤维化速度较慢。此突变能够减少 Aβ 的聚集倾向,进而阻止缓慢原纤化肽的累积。它是阿尔茨海默病中血管及脑内淀粉样沉积物的关键组成部分。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 5 mg | 待询 | 待询 | |
| 50 mg | 待询 | 待询 |
| 产品描述 | (Glu20)-Amyloid β-Protein (1-42) represents a variant of amyloid β-protein (Aβ) that fibrillizes more slowly. This is attributed to the Glu20 mutation, which diminishes Aβ42's tendency to aggregate and inhibits the accumulation of this slowly fibrillizing peptide. Notably, amyloid β-protein serves as the principal constituent of amyloid deposits found in both the vascular system and brain parenchyma in Alzheimer's disease [1] [2]. |
| 别名 | β淀粉样蛋白片段, Beta-淀粉样蛋白片段 |
| 分子量 | 4495.98 |
| 分子式 | C199H309N55O62S |
| CAS No. | 1802086-22-1 |
| Sequence | Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Glu-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala |
| Sequence Short | DAEFRHDSGYEVHHQKLVFEAEDVGSNKGAIIGLMVGGVVIA |
| 存储 |
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