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Anti-PYK2 Antibody (5I30)

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产品编号 TMAC-03478

别名 Related adhesion focal tyrosine kinase, RAFTK2, RAFTK, PYK 2, PTK2B protein tyrosine kinase 2 beta, PTK2B, PTK, Protein-tyrosine kinase 2-beta, Protein Tyrosine Kinase 2 Beta, Protein kinase B, Proline-rich tyrosine kinase 2, PKB, MGC124628, Focal adhesion kinase 2, FAK2_HUMAN, FAK2, FADK2, FADK 2, EC 2.7.10.2, E430023O05Rik, Cell adhesion kinase beta, Calcium-dependent tyrosine kinase, Calcium regulated non receptor proline rich tyrosine kinase, CAK-beta, CAKbeta, CAKB, CADTK

Anti-PYK2 Antibody (5I30) 是一种 Rabbit 抗体，靶向 PYK2。Anti-PYK2 Antibody (5I30) 可用于 ICC/IF,IHC,WB。

Anti-PYK2 Antibody (5I30)

Anti-PYK2 Antibody (5I30)

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产品编号 TMAC-03478 别名 Related adhesion focal tyrosine kinase, RAFTK2, RAFTK, PYK 2, PTK2B protein tyrosine kinase 2 beta, PTK2B, PTK, Protein-tyrosine kinase 2-beta, Protein Tyrosine Kinase 2 Beta, Protein kinase B, Proline-rich tyrosine kinase 2, PKB, MGC124628, Focal adhesion kinase 2, FAK2_HUMAN, FAK2, FADK2, FADK 2, EC 2.7.10.2, E430023O05Rik, Cell adhesion kinase beta, Calcium-dependent tyrosine kinase, Calcium regulated non receptor proline rich tyrosine kinase, CAK-beta, CAKbeta, CAKB, CADTK

Anti-PYK2 Antibody (5I30) 是一种 Rabbit 抗体，靶向 PYK2。Anti-PYK2 Antibody (5I30) 可用于 ICC/IF,IHC,WB。

规格价格库存数量
50 μL
¥ 1,480
5日内发货
100 μL
¥ 2,485
5日内发货
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产品介绍

生物活性
产品描述
Anti-PYK2 Antibody (5I30) is a Rabbit antibody targeting PYK2. Anti-PYK2 Antibody (5I30) can be used in ICC/IF,IHC,WB.
别名Related adhesion focal tyrosine kinase, RAFTK2, RAFTK, PYK 2, PTK2B protein tyrosine kinase 2 beta, PTK2B, PTK, Protein-tyrosine kinase 2-beta, Protein Tyrosine Kinase 2 Beta, Protein kinase B, Proline-rich tyrosine kinase 2, PKB, MGC124628, Focal adhesion kinase 2, FAK2_HUMAN, FAK2, FADK2, FADK 2, EC 2.7.10.2, E430023O05Rik, Cell adhesion kinase beta, Calcium-dependent tyrosine kinase, Calcium regulated non receptor proline rich tyrosine kinase, CAK-beta, CAKbeta, CAKB, CADTK
Ig Type
IgG
克隆号
5I30
交叉反应
Human,Mouse,Rat
验证活性
1. Western blot analysis of PYK2 on mouse brain lysates using anti-PYK2 antibody at 1/1,000 dilution.
2. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-PYK2 antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-PYK2 antibody. Counter stained with hematoxylin.
4. Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-PYK2 antibody. Counter stained with hematoxylin.
5. Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-PYK2 antibody. Counter stained with hematoxylin.
6. Immunohistochemical analysis of paraffin-embedded mouse kidney tissue using anti-PYK2 antibody. Counter stained with hematoxylin.
7. ICC staining PYK2 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
8. ICC staining PYK2 in SHG-44 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
9. ICC staining PYK2 in SH-SY-5Y cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
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应用ICC/IFIHCWB
推荐剂量
WB: 1:1000-2000; IHC: 1:50-200; ICC/IF: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景Focal adhesion kinase (FAK) was initially identified as a substrate for the intrinsic protein tyrosine kinase activity of Src-encoded pp60. The deduced amino acid sequence of FAK p125 has shown it to be a cytoplasmic protein tyrosine kinase whose sequence and structural organization are unique compared to other protein families described. A putative new member of the FAK family, designated PYK2 (proline-rich tyrosine kinase 2), exhibits 61% sequence identity with FAK over its kinase domain. PYK2 (also designated CAKb or RAFTK) is highly expressed in the central nervous system. Activation of the kinase leads to modulation of ion channel function and the activation of the MAPK signaling pathway. PYK2 is rapidly phosphorylated on tyrosine residues in response to stimuli that increase intracellular calcium levels and compounds that activate members of the PKC family of kinases, such as phorbol esters.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
Q14289
化学信息
分子量Theoretical: 116 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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