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Anti-CK20 Antibody (1Y657) (ready to use)

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货号 TMAB-04400

Anti-CK20 Antibody (1Y657) 是一种 Mouse 抗体，靶向 CK20。Anti-CK20 Antibody (1Y657) 可用于 IHC-P,IHC-Fr,ICC/IF,IF。

Anti-CK20 Antibody (1Y657) (ready to use)

Anti-CK20 Antibody (1Y657) (ready to use)

一键复制产品信息
Rating icon 还可以
货号 TMAB-04400

Anti-CK20 Antibody (1Y657) 是一种 Mouse 抗体，靶向 CK20。Anti-CK20 Antibody (1Y657) 可用于 IHC-P,IHC-Fr,ICC/IF,IF。

规格价格库存数量
3 mL
¥ 555
5日内发货
6 mL
¥ 960
5日内发货
库存状态实时更新，以官网显示为准，现货产品可直接加购物车下单
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产品介绍

生物活性
产品描述
Anti-CK20 Antibody (1Y657) is a Mouse antibody targeting CK20. Anti-CK20 Antibody (1Y657) can be used in IHC-P,IHC-Fr,ICC/IF,IF.
Ig Type
IgG2a
克隆号
1Y657
反应种属
Human
应用IHC-PIHC-FrICC/IFIF
抗体种类
Monoclonal
宿主来源Mouse
亚细胞定位Cytoplasm.
组织特异性Expressed predominantly in the intestinal epithelium. Expressed in luminal cells of colonic mucosa. Also expressed in the Merkel cells of keratinized oral mucosa; specifically at the tips of some rete ridges of the gingival mucosa, in the basal layer of the palatal mucosa and in the taste buds of lingual mucosa.
构建方式Hybridoma Monoclonal Antibody
纯化方式Protein G purified
性状Liquid
缓冲液0.01M PBS (pH7.4) with 1% BSA and 0.02% Proclin300.
研究背景Cytokeratin 20 is a type I keratin which is primarily expressed in gastric and intestinal epithelium, urothelium, and Merkel-cells. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Their genes are clustered in a region of chromosome 17q12-q21. Cytokeratin 20 is a major cellular protein of mature enterocytes and goblet cells and is specifically expressed in the gastric and intestinal mucosa. It is also expressed in adenocarcinomas of the colon, stomach, pancreas and the bile system and is present in mucinous ovarian tumors, transitional-cell and Merkel-cell carcinomas. Notably, the squamous cell carcinomas and adenocarcinomas of the breast, lung, and endometrium, non-mucinous tumors of the ovary, and small cell carcinomas lack cytokeratin 20.
抗原信息
免疫原
KLH conjugated synthetic peptide: human CK20
抗原种属
Human
基因名称
KRT20
基因ID
54474
蛋白名称
Keratin, type I cytoskeletal 20
Uniprot ID
P35900
功能
Plays a significant role in maintaining keratin filament organization in intestinal epithelia. When phosphorylated, plays a role in the secretion of mucin in the small intestine (By similarity).
化学信息
分子量Theoretical: 48 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 12 months, do not freeze.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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