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Anti-Pepsinogen C/PGC Antibody (6C563)

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Anti-Pepsinogen C/PGC Antibody (6C563)
产品编号 TMAY-03754
别名 progastricsin (pepsinogen C)

Anti-Pepsinogen C/PGC Antibody (6C563) 是一种 Rabbit 抗体,靶向 Pepsinogen C/PGC。Anti-Pepsinogen C/PGC Antibody (6C563) 可用于 ELISA。

Anti-Pepsinogen C/PGC Antibody (6C563)

Anti-Pepsinogen C/PGC Antibody (6C563)

Rating icon 还可以
Anti-Pepsinogen C/PGC Antibody (6C563)
产品编号 TMAY-03754 别名 progastricsin (pepsinogen C)

Anti-Pepsinogen C/PGC Antibody (6C563) 是一种 Rabbit 抗体,靶向 Pepsinogen C/PGC。Anti-Pepsinogen C/PGC Antibody (6C563) 可用于 ELISA。

规格价格库存数量
100 μL
¥ 2,279
5日内发货
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产品描述
Anti-Pepsinogen C/PGC Antibody (6C563) is a Rabbit antibody targeting Pepsinogen C/PGC. Anti-Pepsinogen C/PGC Antibody (6C563) can be used in ELISA.
别名progastricsin (pepsinogen C)
Ig Type
Rabbit IgG
克隆号
6C563
交叉反应
Rat
应用
推荐剂量
ELISA: 1:5000-1:10000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Rat Pepsinogen C / PGC (rR Pepsinogen C / PGC; TMPY-02513; NP_579818.1; Met1-Val392).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Pepsinogen C, also known as PGC, is an aspartic proteinase that belongs to the peptidase family A1. Pepsinogen C is synthesized in the gastric mucosa as inactive precursors, known as zymogens. Pepsinogen C contains a prosegment that serves to stabilize the inactive form and prevent entry of the substrate to the active site. At low PH conditions, Pepsinogen C undergoes conversion into active enzyme. Pepsinogen C has been found expressed in all regions of the stomach mucosa and also in the proximal duodenal mucosa. In stomach cancer tissues and cancer cell lines, the expressions of the pepsinogen genes were decreased or lost, in good accordance with their pepsinogen productions. No gross structural changes of the pepsinogen genes were observed in these cancers, but the methylation patterns of the pepsinogen genes were found to be altered in different ways in different cancers. Serum levels of Pepsinogen C are used as a biomarker for certain gastric diseases including Helicobacter pylori related gastritis.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Rat Pepsinogen C / PGC Protein (TMPY-02513)
抗原种属
Rat
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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