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Anti-RAMP2 Polyclonal Antibody

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货号 TMAB-12065

Anti-RAMP2 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 RAMP2。Anti-RAMP2 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF,ELISA。

Anti-RAMP2 Polyclonal Antibody

Anti-RAMP2 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-12065

Anti-RAMP2 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 RAMP2。Anti-RAMP2 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF,ELISA。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍


生物活性
产品描述
Anti-RAMP2 Polyclonal Antibody is a Rabbit antibody targeting RAMP2. Anti-RAMP2 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF,ELISA.
Ig Type
IgG
反应种属
Human,Mouse,Rat
应用WBIHC-PIHC-FrIFELISA
推荐剂量
WB: 1:500-2000; IHC-P: 1:50 - 1:200; IHC-Fr: 1:50 - 1:200; IF: 1:50 - 1:200; ELISA: 1:5000-10000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell Membrane; Single-pass type I membrane protein
组织特异性Strongly expressed in lung, breast, immune system and fetal tissues.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP2) protein, CRLR functions as an adrenomedullin receptor. The RAMP2 protein is involved in core glycosylation and transportation of adrenomedullin receptor to the cell surface.
抗原信息
免疫原
KLH conjugated synthetic peptide: human RAMP2
抗原种属
Human
基因名称
RAMP2
基因ID
蛋白名称
Receptor activity-modifying protein 2
Uniprot ID
功能
RAMP2 (Receptor activity-modifying protein 2) transports the calcitonin gene-related peptide type 1 receptor (CALCRL) to the plasma membrane. RAMP2 acts as a receptor for adrenomedullin (AM) together with CALCRL. Co-expression of Receptor activity-modifying protein 2 (RAMP2) with the calcitonin-receptor-like-receptor (CRLR) results in the production of a functional adrenomedullin (ADM) receptor. RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor. RAMP2 is a heterodimer of CALCRL and RAMP2. RAMP2 is strongly expressed in lung, breast, immune system and fetal tissues. RAMP2 belongs to the RAMP family.
化学信息
分子量Theoretical: 15 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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