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Anti-RAMP2 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 RAMP2。Anti-RAMP2 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF,ELISA。
Anti-RAMP2 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 RAMP2。Anti-RAMP2 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF,ELISA。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,170 | 5日内发货 | |
| 100 μL | ¥ 1,975 | 5日内发货 | |
| 200 μL | ¥ 2,785 | 5日内发货 |
| 产品描述 | Anti-RAMP2 Polyclonal Antibody is a Rabbit antibody targeting RAMP2. Anti-RAMP2 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF,ELISA. |
| Ig Type | IgG |
| 反应种属 | Human,Mouse,Rat |
| 应用 | WBIHC-PIHC-FrIFELISA |
| 推荐剂量 | WB: 1:500-2000; IHC-P: 1:50 - 1:200; IHC-Fr: 1:50 - 1:200; IF: 1:50 - 1:200; ELISA: 1:5000-10000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cell Membrane; Single-pass type I membrane protein |
| 组织特异性 | Strongly expressed in lung, breast, immune system and fetal tissues. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP2) protein, CRLR functions as an adrenomedullin receptor. The RAMP2 protein is involved in core glycosylation and transportation of adrenomedullin receptor to the cell surface. |
| 免疫原 | KLH conjugated synthetic peptide: human RAMP2 |
| 抗原种属 | Human |
| 基因名称 | RAMP2 |
| 基因ID | |
| 蛋白名称 | Receptor activity-modifying protein 2 |
| Uniprot ID | |
| 功能 | RAMP2 (Receptor activity-modifying protein 2) transports the calcitonin gene-related peptide type 1 receptor (CALCRL) to the plasma membrane. RAMP2 acts as a receptor for adrenomedullin (AM) together with CALCRL. Co-expression of Receptor activity-modifying protein 2 (RAMP2) with the calcitonin-receptor-like-receptor (CRLR) results in the production of a functional adrenomedullin (ADM) receptor. RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor. RAMP2 is a heterodimer of CALCRL and RAMP2. RAMP2 is strongly expressed in lung, breast, immune system and fetal tissues. RAMP2 belongs to the RAMP family. |
| 分子量 | Theoretical: 15 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |