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Anti-BACE1 Antibody (2Z488) 是一种 Mouse 抗体,靶向 BACE1。Anti-BACE1 Antibody (2Z488) 可用于 ELISA。
Anti-BACE1 Antibody (2Z488) 是一种 Mouse 抗体,靶向 BACE1。Anti-BACE1 Antibody (2Z488) 可用于 ELISA。
产品描述 | Anti-BACE1 Antibody (2Z488) is a Mouse antibody targeting BACE1. Anti-BACE1 Antibody (2Z488) can be used in ELISA. |
Ig Type | Monoclonal Mouse IgG1 |
克隆号 | 2Z488 |
交叉反应 | Human |
应用 | ELISA |
推荐剂量 | ELISA: 1:1000-1:2000 |
抗体种类 | Monoclonal |
宿主来源 | Mouse |
构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human ALK-1 / ACVRL1 (rh ALK-1 / ACVRL1 ; TMPY-01168; NP_000011.2; Met1-Gln118). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | Activin A receptor, type II-like 1 (ACVRL1), also known as ALK-1 (activin receptor-like kinase 1), is an endothelial-specific type I receptor of the TGF-beta (transforming growth factor beta) receptor family of ligands. On ligand binding, a heteromeric receptor complex forms consisting of two type II and two type I transmembrane serine/threonine kinases. ACVRL1 protein is expressed in certain blood vessels of kidney, spleen, heart and intestine, serving as an important role during vascular development. Mutations in ACVRL1 gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2 and vascular disease. |
偶联 | Unconjugated |
免疫原 | Recombinant Human ALK-1 / ACVRL1 Protein (TMPY-01168) |
抗原种属 | Human |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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