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Anti-CD48 Antibody (1M803)

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产品编号 TMAY-03285

Anti-CD48 Antibody (1M803) 是一种 Rabbit 抗体,靶向 CD48。Anti-CD48 Antibody (1M803) 可用于 ELISA(Det),FCM,ICC/IF。

Anti-CD48 Antibody (1M803)

Anti-CD48 Antibody (1M803)

Rating icon 还可以
产品编号 TMAY-03285

Anti-CD48 Antibody (1M803) 是一种 Rabbit 抗体,靶向 CD48。Anti-CD48 Antibody (1M803) 可用于 ELISA(Det),FCM,ICC/IF。

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产品介绍

生物活性
产品描述
Anti-CD48 Antibody (1M803) is a Rabbit antibody targeting CD48. Anti-CD48 Antibody (1M803) can be used in ELISA(Det),FCM,ICC/IF.
Ig Type
Monoclonal Rabbit IgG
克隆号
1M803
交叉反应
Mouse
验证活性
1. Immunofluorescence staining of Mouse CD48 in Mouse Spleen cells. Cells were fixed with 4% PFA, blocked with 10% serum, and incubated with rabbit anti-mouse CD48 monoclonal antibody (1:60) at 37°C 1 hour. Then cells were stained with the Alexa Fluor® 488-conjugated Goat Anti-rabbit IgG secondary antibody (green). Positive staining was localized to cell membrane.

2. Flow cytometric analysis of Mouse CD48 expression on BABL/c splenocytes. Cells were stained with purified anti-Mouse CD48, then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.
应用
ELISA(Det),FCM,ICC/IF
推荐剂量
ICC-IF: 1:20-1:100; FCM: 1:25-1:100; ELISA(Det): 1:1000-1:10000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Mouse CD48 / SLAMF2 (rM CD48 / SLAMF2; TMPY-01372; NP_031675.1; Met1-Arg216).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Cluster of Differentiation 48 (CD48), also known as SLAMF2, BCM-1 and BLAST-1, is a GPI-linked protein belonging to the CD2 subfamily of immunoglobulin superfamily molecules. CD2 and 2B4 (CD244) are known ligands for CD48. CD48 protein is expressed on most lineage-committed hematopoietic cells but not on hematopoietic stem cells or multipotent hematopoietic progenitors. CD48 protein performs biological functions in a variety processes including adhesion, pathogen recognition, cellular activation, and cytokine regulation, and emerges as a critical effector molecule in immune responses.Cancer ImmunotherapyCo-inhibitory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: AntibodiesImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: FCM AntibodiesImmune Checkpoint Detection: ICC AntibodiesImmune Checkpoint Detection: IHC AntibodiesImmune Checkpoint Detection: IP AntibodiesImmune Checkpoint Detection: WB AntibodiesImmune Checkpoint ProteinsImmune Checkpoint TargetsImmunotherapyTargeted Therapy
偶联与修饰
偶联
Unconjugated
其他可选修饰符
APC/PerCP/FITC/HRP/PE
可提供抗体种类
6
抗原信息
免疫原
Recombinant Mouse CD48 / SLAMF2 protein (TMPY-01372)
抗原种属
Mouse
研究领域
Cancer Drug Targets
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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