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Anti-FOXP3 Antibody (2R607)

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Anti-FOXP3 Antibody (2R607)
产品编号 TMAY-01586

Anti-FOXP3 Antibody (2R607) 是一种 Mouse 抗体,靶向 FOXP3。Anti-FOXP3 Antibody (2R607) 可用于 IHC-P。

Anti-FOXP3 Antibody (2R607)

Anti-FOXP3 Antibody (2R607)

Rating icon 还可以
Anti-FOXP3 Antibody (2R607)
产品编号 TMAY-01586

Anti-FOXP3 Antibody (2R607) 是一种 Mouse 抗体,靶向 FOXP3。Anti-FOXP3 Antibody (2R607) 可用于 IHC-P。

规格价格库存数量
100 μL
¥ 1,684
5日内发货
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TargetMol 的所有产品仅用作科学研究或药证申报,不能被用于人体,我们不向个人提供产品和服务。请您遵守承诺用途,不得违反法律法规规定用于任何其他用途。
实验操作小课堂
常见问题解答
化合物带有盐酸盐离子、硫酸盐离子等是否和其本身有什么区别?盐形式和游离态有什么区别?
盐和非盐形式化合物的活性分子是一样的,在生物实验中起到的效果也一致,活性和使用方法都是一样的。只是由于呈盐不同,物理性质比如溶解度会有差异。建议您根据溶解、实验需求进行选择。
如何选择某个靶点的特异性或总的抑制剂?特异性和非特异性的区别是什么?
抑制剂按照特异性分为广谱 pan 和特异性 selective 两种。Pan 为某个靶点总的抑制剂,对所有亚型或整个家族的成员都有抑制作用。Selective 抑制剂针对某个蛋白激酶的某个亚型或家族中某个成员抑制率特别高或有特异性抑制作用。 一般评价一个抑制剂的抑制效率主要看 IC50 值,IC50 值越低,说明抑制剂效率越高。建议您根据以上几个特征进行综合选择,也可联系技术帮您推荐相关抑制剂。
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产品介绍

生物活性
产品描述
Anti-FOXP3 Antibody (2R607) is a Mouse antibody targeting FOXP3. Anti-FOXP3 Antibody (2R607) can be used in IHC-P.
Ig Type
mouse IgG2a
克隆号
2R607
交叉反应
Human
验证活性
Immunochemical staining of human FOXP3 in human carcinoma of sigmoid with mouse monoclonal antibody at 1:200 dilution, formalin-fixed paraffin embedded sections.
应用
IHC-P
推荐剂量
IHC-P: 1:100-1:500
抗体种类
Monoclonal
宿主来源Mouse
构建方式This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, a synthetic peptide corresponding to the center region of the human FOXP3. The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Forkhead box P3 (FOXP3) is a key gene in the immune system which also plays a role in tumor development. The Treg cell lineage-specification factor FOXP3 (forkhead box P3) is essential for Treg cells' ability to uphold immunologic tolerance. Forkhead box protein 3 (FOXP3) is expressed in numerous types of tumor cell and is associated with tumor progression and prognosis. which had been reported that FOXP3 inhibited cellular proliferation and induced apoptosis of gastric cancer (GC) cells by activating the apoptosis signaling pathway. The elevated expression of FOXP3 in blood and urine samples from kidney transplant recipients could be a useful noninvasive biomarker to diagnose graft dysfunction. Forkhead box P3 (FOXP3), an X-linked tumor suppressor gene, plays an important role in breast cancer.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
A synthetic peptide: center region of the Human FOXP3
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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