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Anti-UBE2L6 Antibody (3D788)

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产品编号 TMAY-02404

Anti-UBE2L6 Antibody (3D788) 是一种 Rabbit 抗体,靶向 UBE2L6。Anti-UBE2L6 Antibody (3D788) 可用于 ELISA。

Anti-UBE2L6 Antibody (3D788)

Anti-UBE2L6 Antibody (3D788)

Rating icon 还可以
产品编号 TMAY-02404

Anti-UBE2L6 Antibody (3D788) 是一种 Rabbit 抗体,靶向 UBE2L6。Anti-UBE2L6 Antibody (3D788) 可用于 ELISA。

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产品介绍

生物活性
产品描述
Anti-UBE2L6 Antibody (3D788) is a Rabbit antibody targeting UBE2L6. Anti-UBE2L6 Antibody (3D788) can be used in ELISA.
Ig Type
Monoclonal Rabbit IgG
克隆号
3D788
交叉反应
Human
应用
ELISA
推荐剂量
ELISA: 1:5000-1:10000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human UBCH8 / UBE2L6 (rh UBCH8 / UBE2L6; TMPY-02842; O14933-1; Met1-Ser153).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景UBCH8, also known as UBE2L6, belongs to the ubiquitin-conjugating enzyme family. The family of ubiquitin-conjugating (E2) enzymes is characterized by the presence of a highly conserved ubiquitin-conjugating (UBC) domain. These domains accommodate the ATP-activated ubiquitin (Ub) or ubiquitin-like (UBL) protein via a covalently linked thioester onto its active-site residue. E2 enzymes act via selective protein-protein interactions with the E1 and E3 enzymes and connect activation to covalent modification. By doing so, E2s differentiate effects on downstream substrates, either with a single Ub/UBL molecule or as a chain. UBCH8 is highly similar in primary structure to the enzyme encoded by the UBE2L3 gene. It catalyzes the covalent attachment of ubiquitin or ISG15 to other proteins. UBCH8 functions in the E6/E6-AP-induced ubiquitination of p53/TP53 and promotes ubiquitination and subsequent proteasomal degradation of FLT3. At protein level, it is present in natural killer cells.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Human UBCH8 / UBE2L6 protein (TMPY-02842)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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