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Anti-BLVRB Antibody (9A653)

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Anti-BLVRB Antibody (9A653)
产品编号 TMAY-02513
别名 SDR43U1, HEL-S-10, FLR, BVRB, biliverdin reductase B

Anti-BLVRB Antibody (9A653) 是一种 Mouse 抗体，靶向 BLVRB。Anti-BLVRB Antibody (9A653) 可用于 WB。

Anti-BLVRB Antibody (9A653)
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Anti-BLVRB Antibody (9A653)

Rating icon 还可以
Anti-BLVRB Antibody (9A653)
产品编号 TMAY-02513 别名 SDR43U1, HEL-S-10, FLR, BVRB, biliverdin reductase B

Anti-BLVRB Antibody (9A653) 是一种 Mouse 抗体，靶向 BLVRB。Anti-BLVRB Antibody (9A653) 可用于 WB。

规格价格库存数量
100 μL
¥ 1,679
5日内发货
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产品介绍

生物活性
产品描述
Anti-BLVRB Antibody (9A653) is a Mouse antibody targeting BLVRB. Anti-BLVRB Antibody (9A653) can be used in WB.
别名SDR43U1, HEL-S-10, FLR, BVRB, biliverdin reductase B
Ig Type
Mouse IgG2a
克隆号
9A653
交叉反应
Human
验证活性
Anti-BLVRB mouse monoclonal antibody at 1:500 dilution.
-Lane A: K562 Whole Cell lysate.
-Lysates/proteins at 30 μg per lane.
-Secondary
-Goat Anti-Mouse IgG H&L (Dylight800) at 1/15000 dilution.
-Developed using the Odyssey technique.
-Performed under reducing conditions.
-Predicted band size:22 kDa.
-Observed band size:22 kDa
应用
WB
推荐剂量
WB: 1:500-1:2000
抗体种类
Monoclonal
宿主来源Mouse
构建方式This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human BLVRB / biliverdin reductase B (rh BLVRB / biliverdin reductase B; TMPY-02519; P30043; Ala2-Gln206). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Biliverdin reductase (hBVR) is a serine/threonine kinase that catalyzes reduction of the heme oxygenase (HO) activity product, biliverdin, to bilirubin. BVR consists of an N-terminal dinucleotide-binding domain (Rossmann-fold) and a C-terminal domain that contains a six-stranded β-sheet that is flanked on one face by several α-helices. The C-terminal and N-terminal domains interact extensively, forming the active site cleft at their interface. Biliverdin reductase (BVR) catalyzes the last step in heme degradation by reducing the γ-methene bridge of the open tetrapyrrole, biliverdin IXα, to bilirubin with the concomitant oxidation of a β-nicotinamide adenine dinucleotide (NADH) or β-nicotinamide adenine dinucleotide phosphate (NADPH) cofactor. It is now recognized that human BVR (hBVR) is a dual-specificity kinase (Ser / Thr and Tyr) upstream activator of the insulin/insulin growth factor-1 (IGF-1) and mitogen-activated protein kinase (MAPK) signaling pathways. Human BVR (hBVR) is essential for MAPK-extracellular signal-regulated kinase (ERK)1/2 (MEK)-eukaryotic-like protein kinase (Elk) signaling and has been identified as the cytoplasm-nuclear heme transporter of ERK1/2 and hematin, the key components of stress-responsive gene expression.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Human BLVRB / biliverdin reductase B protein (TMPY-02519)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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