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Anti-HSD17B11 Polyclonal Antibody

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货号 TMAB-07318

Anti-HSD17B11 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 HSD17B11。Anti-HSD17B11 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-HSD17B11 Polyclonal Antibody

Anti-HSD17B11 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-07318

Anti-HSD17B11 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 HSD17B11。Anti-HSD17B11 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-HSD17B11 Polyclonal Antibody is a Rabbit antibody targeting HSD17B11. Anti-HSD17B11 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Rat (predicted:Human,Mouse,Pig,Cow,Horse,Rabbit,Sheep)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Secreted.
组织特异性Present at high level in steroidogenic cells such as syncytiotrophoblasts, sebaceous gland, Leydig cells, and granulosa cells of the dominant follicle and corpus luteum. In lung, it is detected in the ciliated epithelium and in acini of adult trachea, in bronchioles, but not in alveoli. In the eye, it is detected in the nonpigmented epithelium of the ciliary body and, at lower level, in the inner nuclear layer of the retina (at protein level). Widely expressed. Highly expressed in retina, pancreas, kidney, liver, lung, adrenal, small intestine, ovary and heart.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Short-chain alcohol dehydrogenases, such as HSD17B11, metabolize secondary alcohols and ketones (Brereton et al., 2001 [PubMed 11165019]).[supplied by OMIM, Jun 2009]
抗原信息
免疫原
KLH conjugated synthetic peptide: human Hsd17b11
抗原种属
Human
基因名称
HSD17B11
基因ID
51170
蛋白名称
Estradiol 17-beta-dehydrogenase 11
Uniprot ID
Q8NBQ5
功能
Can convert androstan-3-alpha,17-beta-diol (3-alpha-diol) to androsterone in vitro, suggesting that it may participate in androgen metabolism during steroidogenesis. May act by metabolizing compounds that stimulate steroid synthesis and/or by generating metabolites that inhibit it. Has no activity toward DHEA (dehydroepiandrosterone), or A-dione (4-androste-3,17-dione), and only a slight activity toward testosterone to A-dione. Tumor-associated antigen in cutaneous T-cell lymphoma.
化学信息
分子量Theoretical: 31 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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