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Anti-PIK3CA Antibody (8O55)

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Anti-PIK3CA Antibody (8O55)
产品编号 TMAC-03285
别名 Phosphoinositide-3-kinase catalytic a polypeptide, Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha (PtdIns-3-kinase subunit p110-alpha, p110alpha)

Anti-PIK3CA Antibody (8O55) 是一种 Rabbit 抗体，靶向 PIK3CA。Anti-PIK3CA Antibody (8O55) 可用于 WB,ICC/IF,IP。

Anti-PIK3CA Antibody (8O55)

Anti-PIK3CA Antibody (8O55)

Rating icon 还可以
Anti-PIK3CA Antibody (8O55)
产品编号 TMAC-03285 别名 Phosphoinositide-3-kinase catalytic a polypeptide, Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha (PtdIns-3-kinase subunit p110-alpha, p110alpha)

Anti-PIK3CA Antibody (8O55) 是一种 Rabbit 抗体，靶向 PIK3CA。Anti-PIK3CA Antibody (8O55) 可用于 WB,ICC/IF,IP。

规格价格库存数量
50 μL
¥ 1,485
5日内发货
100 μL
¥ 2,495
5日内发货
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产品介绍

生物活性
产品描述
Anti-PIK3CA Antibody (8O55) is a Rabbit antibody targeting PIK3CA. Anti-PIK3CA Antibody (8O55) can be used in WB,ICC/IF,IP.
别名Phosphoinositide-3-kinase catalytic a polypeptide, Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha (PtdIns-3-kinase subunit p110-alpha, p110alpha)
Ig Type
IgG
交叉反应
Human,Mouse,Rat
验证活性
1. ICC staining PI 3 kinase p110 alpha in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
2. ICC staining PI 3 kinase p110 alpha in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
3. ICC staining PI 3 kinase p110 alpha in MCF-7 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
应用
WB
ICC/IF
IP
推荐剂量
WB: 1:500-1000; ICC/IF: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景Phosphatidylinositol 3-kinase (PI 3-kinase) is composed of p85 and p110 subunits. p85 lacks PI 3-kinase activity and acts as an adapter, coupling p110 to activated protein tyrosine kinase. Two forms of p85 have been described (p85α and p85β), each possessing one SH3 and two SH2 domains. Various p110 isoforms have been identified. p110α and p110β interact with p85α, and p110α has also been shown to interact with p85β in vitro. p110δ expression is restricted to white blood cells. It has been shown to bind p85α and β, but it apparently does not phosphorylate these subunits. p110δ seems to have the capacity to autophosphorylate. p110γ does not interact with the p85 subunits. It has been shown to be activated by α and βγ heterotrimeric G proteins.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
P42336
化学信息
分子量Theoretical: 124 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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关键词

Serine/threonine protein kinase PIK3CAPtdIns-3-kinase subunit αPtdIns-3-kinase subunit alphaPtdIns-3-kinase subunit aPIK3CAPI3K-αPI3KαPI3-kinase subunit αPI3-kinase subunit alphaPI3-kinase subunit aPI3K-alphaPI3KalphaPI3K-aPI3KaPhosphoinositide-3-kinase catalytic α polypeptidePhosphoinositide-3-kinase catalytic alpha polypeptidePhosphoinositide 3-kinase αPhosphoinositide 3-kinase alphaPhosphoinositide 3-kinase aPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit α isoformPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoformPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit a isoformPhosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit α (PtdIns-3-kinase subunit p110-αPhosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit a (PtdIns-3-kinase subunit p110-ap110α)p110αp110alphap110a)p110ap110 αp110 alphap110 a5-bisphosphate 3-kinase catalytic subunit α isoform5-bisphosphate 3-kinase catalytic subunit alpha isoform5-bisphosphate 3-kinase catalytic subunit a isoform

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