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顶部产品介绍偶联与修饰储存和溶解信息计算器

Anti-Atezolizumab Antibody (1C27)

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货号 TMAS-00008

别名 Tecentriq

Anti-Atezolizumab Antibody (1C27) 是一种 Mouse 抗体，靶向 Atezolizumab。Anti-Atezolizumab Antibody (1C27) 可用于 ELISA。

Anti-Atezolizumab Antibody (1C27)

Anti-Atezolizumab Antibody (1C27)

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Rating icon 还可以
货号 TMAS-00008 别名 Tecentriq

Anti-Atezolizumab Antibody (1C27) 是一种 Mouse 抗体，靶向 Atezolizumab。Anti-Atezolizumab Antibody (1C27) 可用于 ELISA。

规格价格库存数量
40 μg
¥ 1,609
5日内发货
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产品介绍

生物活性
产品描述
Anti-Atezolizumab Antibody (1C27) is a Mouse antibody targeting Atezolizumab. Anti-Atezolizumab Antibody (1C27) can be used in ELISA.
别名Tecentriq
Ig Type
IgG1,κ
克隆号
1C27
特异性
The product is specific for Atezolizumab. The antibody is recommended as a capture antibody in a pharmacokinetic (PK) bridging assay with detection antibody Anti-Atezolizumab Antibody-Biotin (9K295) (TMAS-00009B).
应用ELISA
推荐剂量
ELISA: 0.01-1 µg/ml
抗体种类
Monoclonal
宿主来源Mouse
纯化方式Protein A affinity column
性状Lyophilized. Reconstitute the lyophilized powder with deionized water (or equivalent) to a final concentration of 0.5 mg/mL.
缓冲液Lyophilized with PBS, pH 7.4, containing 0.02% sodium azide.
研究背景Atezolizumab is a fully humanized, engineered monoclonal antibody of IgG1 isotype against the protein programmed cell death-ligand 1 (PD-L1). Atezolizumab blocks the interaction of PD-L1 with programmed cell death protein 1 (PD-1) and CD80 receptors (B7-1Rs). PD-L1 can be highly expressed on certain tumors, which is thought to lead to reduced activation of immune cells (cytotoxic T-cells in particular) that might otherwise recognize and attack the cancer. Inhibition of PD-L1 by atezolizumab can remove this inhibitor effect and thereby engender an anti-tumor response. It is one of several ways to block inhibitory signals related to T-cell activation, a more general strategy known as "immune checkpoint inhibition."
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Atezolizumab
储存&溶解度
储存方式The lyophilized product store at -20°C or -80°C for 12 months. The reconstituted antibody can be stored at 2°C-8°C for 2-3 weeks or at -20°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储-20°C for 1 year

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