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CSPG4 Protein, Human, Recombinant (His & Myc)

CSPG4 Protein, Human, Recombinant (His & Myc)

产品编号 TMPH-01086
别名: MCSP, Melanoma chondroitin sulfate proteoglycan, Chondroitin sulfate proteoglycan 4, Chondroitin sulfate proteoglycan NG2, CSPG4, Melanoma-associated chondroitin sulfate proteoglycan

CSPG4 Protein, Human, Recombinant (His & Myc) is expressed in HEK293 mammalian cells with N-10xHis and C-Myc tag. The predicted molecular weight is 73.2 kDa and the accession number is Q6UVK1.

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CSPG4 Protein, Human, Recombinant (His & Myc)
规格 价格/CNY 货期 数量
20 μg ¥ 3,910 20日内发货
100 μg ¥ 10,900 20日内发货
1 mg ¥ 46,000 20日内发货
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产品目录号及名称: CSPG4 Protein, Human, Recombinant (His & Myc) (TMPH-01086)
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产品描述 CSPG4 Protein, Human, Recombinant (His & Myc) is expressed in HEK293 mammalian cells with N-10xHis and C-Myc tag. The predicted molecular weight is 73.2 kDa and the accession number is Q6UVK1.
种属 Human
表达系统 HEK293 Cells
标签 N-10xHis, C-Myc
蛋白编号 Q6UVK1
别名 MCSP, Melanoma chondroitin sulfate proteoglycan, Chondroitin sulfate proteoglycan 4, Chondroitin sulfate proteoglycan NG2, CSPG4, Melanoma-associated chondroitin sulfate proteoglycan
氨基酸序列 SLKGSQTLTVCPGSVQPLSSQTLRASSSAGTDPQLLLYRVVRGPQLGRLFHAQQDSTGEALVNFTQAEVYAGNILYEHEMPPEPFWEAHDTLELQLSSPPARDVAATLAVAVSFEAACPQRPSHLWKNKGLWVPEGQRARITVAALDASNLLASVPSPQRSEHDVLFQVTQFPSRGQLLVSEEPLHAGQPHFLQSQLAAGQLVYAHGGGGTQQDGFHFRAHLQGPAGASVAGPQTSEAFAITVRDVNERPPQPQASVPLRLTRGSRAPISRAQLSVVDPDSAPGEIEYEVQRAPHNGFLSLVGGGLGPVTRFTQADVDSGRLAFVANGSSVAGIFQLSMSDGASPPLPMSLAVDILPSAIEVQLRAPLEVPQALGRSSLSQQQLRVVSDREEPEAAYRLIQGPQYGHLLVGGRPTSAFSQFQIDQGEVVFAFTNFSSSHDHFRVLALARGVNASAVVNVTVRALLHVWAGGPWPQGATLRLDPTVLDAGELANRTGSVPRFRLLEGPRHGRVVRVPRARTEPGGSQLVEQFTQQDLEDGRLGLEVGRPEGRAPGPAGDSLTLELWAQGVPPAVASLDFATEPYNAARPYSVALLSVPEAARTEAGKPESSTPTGEPGPMASSPEPAVAKGGFLSFLEANMFS
蛋白构建 1583-2224 aa
蛋白纯度 > 85% as determined by SDS-PAGE.
分子量 73.2 kDa (predicted)
缓冲液 Tris-based buffer, 50% glycerol
复溶方法 A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

研究背景 Proteoglycan playing a role in cell proliferation and migration which stimulates endothelial cells motility during microvascular morphogenesis. May also inhibit neurite outgrowth and growth cone collapse during axon regeneration. Cell surface receptor for collagen alpha 2(VI) which may confer cells ability to migrate on that substrate. Binds through its extracellular N-terminus growth factors, extracellular matrix proteases modulating their activity. May regulate MPP16-dependent degradation and invasion of type I collagen participating in melanoma cells invasion properties. May modulate the plasminogen system by enhancing plasminogen activation and inhibiting angiostatin. Functions also as a signal transducing protein by binding through its cytoplasmic C-terminus scaffolding and signaling proteins. May promote retraction fiber formation and cell polarization through Rho GTPase activation. May stimulate alpha-4, beta-1 integrin-mediated adhesion and spreading by recruiting and activating a signaling cascade through CDC42, ACK1 and BCAR1. May activate FAK and ERK1/ERK2 signaling cascades.

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Keywords

CSPG4 Protein, Human, Recombinant (His & Myc) MCSP Melanoma chondroitin sulfate proteoglycan Chondroitin sulfate proteoglycan 4 Chondroitin sulfate proteoglycan NG2 CSPG4 Melanoma-associated chondroitin sulfate proteoglycan recombinant recombinant-proteins proteins protein

 

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