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AXL Protein, Human, Recombinant (aa 33-442, His)

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产品编号 TMPY-01601U

AXL Protein, Human, Recombinant (aa 33-442, His) is expressed in HEK293 Cells. The accession number is NP_068713.2.

AXL Protein, Human, Recombinant (aa 33-442, His)

一键复制产品信息

产品编号 TMPY-01601U

AXL Protein, Human, Recombinant (aa 33-442, His) is expressed in HEK293 Cells. The accession number is NP_068713.2.

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产品信息

生物活性	Immobilized Human AXL, His Tag at 1 μg/ml (100 μl/well) on the plate. Dose response curve for Anti-AXL Antibody, hFc Tag with the EC50 of 10.0 ng/ml determined by ELISA.
产品描述	AXL Protein, Human, Recombinant (aa 33-442, His) is expressed in HEK293 Cells. The accession number is NP_068713.2.
种属	Human
表达系统	HEK293 Cells
标签	C-His
蛋白编号	NP_068713.2
别名	UFO,Tyro7,JTK11,AXL receptor tyrosine kinase,ARK
蛋白构建	Glu33-Ser442
蛋白纯度	> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
分子量	45.4 kDa (Predicted); 65-75 kDa (Due to glycosylation)
内毒素	< 1.0 EU/μg of the protein as determined by the LAL method.
蛋白性状	Lyophilized powder
缓冲液	Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
存储	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
研究背景	Axl, a member of the TAM (Tyro3, Axl, Mer) family, and its inhibitors can specifically break the kinase signaling nodes, allowing advanced patients to regain drug sensitivity with improved therapeutic efficacy. Overexpression and activation of Axl receptor tyrosine kinase have been widely accepted to promote cell proliferation, chemotherapy resistance, invasion, and metastasis in several human cancers, such as lung, breast, and pancreatic cancers.