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顶部生物活性储存和溶解信息计算器

Anti-OTUB2 Antibody (4V813)

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产品编号 TMAY-02522
别名 OTU2, OTU deubiquitinase, ubiquitin aldehyde binding 2, OTB2, C14orf137

Anti-OTUB2 Antibody (4V813) 是一种 Rabbit 抗体，靶向 OTUB2。Anti-OTUB2 Antibody (4V813) 可用于 ELISA,ICC/IF。

Anti-OTUB2 Antibody (4V813)

Anti-OTUB2 Antibody (4V813)

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产品编号 TMAY-02522 别名 OTU2, OTU deubiquitinase, ubiquitin aldehyde binding 2, OTB2, C14orf137

Anti-OTUB2 Antibody (4V813) 是一种 Rabbit 抗体，靶向 OTUB2。Anti-OTUB2 Antibody (4V813) 可用于 ELISA,ICC/IF。

规格价格库存数量
100 μL
¥ 2,284
5日内发货
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产品介绍

生物活性
产品描述
Anti-OTUB2 Antibody (4V813) is a Rabbit antibody targeting OTUB2. Anti-OTUB2 Antibody (4V813) can be used in ELISA,ICC/IF.
别名OTU2, OTU deubiquitinase, ubiquitin aldehyde binding 2, OTB2, C14orf137
Ig Type
Rabbit IgG
克隆号
4V813
交叉反应
Human
特异性
Human OTUB2
验证活性
Immunofluorescence staining of Human OTUB2 in A549 cells. Cells were fixed with 4% PFA, permeabilzed with 0.3% Triton X-100 in PBS, blocked with 10% serum, and incubated with rabbit anti-Human OTUB2 monoclonal antibody (1:60) at 4°C overnight. Then cells were stained with the Alexa Fluor® 549-conjugated Goat Anti-rabbit IgG secondary antibody (red). Positive staining was localized to cytoplasm and nucleus.
应用ELISAICC/IF
推荐剂量
ELISA: 1:5000-1:10000; ICC-IF: 1:20-1:100
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human OTUB2 (rh OTUB2; TMPY-02522; Q96DC9-1; Met1-His234).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Otubain 2 (OTUB2) is a member of DUBs that belong to the ovarian tumour (OTU) superfamily of proteins which consists of a five-stranded β-sheet sandwiched in between a small helical amino-terminal region consisting of α1 and α2, and a large helical region comprised of α3-α10. Like other DUBs, otubain 2 (OTUB2) cleaves proteins precisely at the ubiquitin-protein bond so that ubiquitylation process can be reversed and regulated. Otubain 2 (OTUB2)'s active-site cleft is sterically occluded by a novel loop conformation resulting in an oxyanion hole, which consists uniquely of backbone amides. Furthermore, the residues that orient and stabilize the active-site histidine of otubain 2 (OTUB2) are different from other cysteine proteases. This reorganization of the active-site topology provides a possible explanation for the low turnover and substrate specificity of the otubains.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Human OTUB2 Protein (TMPY-02522)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

计算器

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关键词

OTU-2OTU 2OTB-2OTB 2

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