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Anti-KDM5A Polyclonal Antibody

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货号 TMAB-07978

Anti-KDM5A Polyclonal Antibody 是一种 Rabbit 抗体,靶向 KDM5A。Anti-KDM5A Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-KDM5A Polyclonal Antibody

Anti-KDM5A Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-07978

Anti-KDM5A Polyclonal Antibody 是一种 Rabbit 抗体,靶向 KDM5A。Anti-KDM5A Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍


生物活性
产品描述
Anti-KDM5A Polyclonal Antibody is a Rabbit antibody targeting KDM5A. Anti-KDM5A Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,Sheep)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus > nucleolus. Occupies promoters of genes involved in RNA metabolism and mitochondrial function.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene encodes a member of the Jumonji, AT-rich interactive domain 1 (JARID1) histone demethylase protein family. The encoded protein plays a role in gene regulation through the histone code by specifically demethylating lysine 4 of histone H3. The encoded protein interacts with many other proteins, including retinoblastoma protein, and is implicated in the transcriptional regulation of Hox genes and cytokines. This gene may play a role in tumor progression. [provided by RefSeq, Aug 2013]
抗原信息
免疫原
KLH conjugated synthetic peptide: human KDM5A
抗原种属
Human
基因名称
KDM5A
基因ID
蛋白名称
Lysine-specific demethylase 5A
Uniprot ID
功能
Histone demethylase that specifically demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'. May stimulate transcription mediated by nuclear receptors. May be involved in transcriptional regulation of Hox proteins during cell differentiation. May participate in transcriptional repression of cytokines such as CXCL12.
化学信息
分子量Theoretical: 192 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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