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Anti-Phospho-AMPK β1 (Ser181) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-AMPK β1 (Ser181)。Anti-Phospho-AMPK β1 (Ser181) Polyclonal Antibody 可用于 WB。
Anti-Phospho-AMPK β1 (Ser181) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-AMPK β1 (Ser181)。Anti-Phospho-AMPK β1 (Ser181) Polyclonal Antibody 可用于 WB。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,480 | 5日内发货 | |
100 μL | ¥ 2,245 | 5日内发货 |
产品描述 | Anti-Phospho-AMPK β1 (Ser181) Polyclonal Antibody is a Rabbit antibody targeting Phospho-AMPK β1 (Ser181). Anti-Phospho-AMPK β1 (Ser181) Polyclonal Antibody can be used in WB. |
别名 | p-AMPK β1 (Ser181), p-AMPK β1 (S181), AMPK β1 (p-Ser181), AMPK β1 (p-S181) |
Ig Type | IgG |
交叉反应 | Human,Mouse,Rat |
验证活性 | 1. Western blot analysis of extracts from Rat kindey using AMPK β1(Phospho-Ser181) Antibody TMAC-00181.The lane on the right is treated with the antigen-specific peptide. |
应用 | |
抗体种类 | Polyclonal |
宿主来源 | Rabbit |
构建方式 | Polyclonal Antibody |
纯化方式 | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
性状 | Liquid |
缓冲液 | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
研究背景 | Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3). |
偶联 | Unconjugated |
其他可选修饰符 | Phospho |
免疫原 | Peptide sequence around phosphorylation site of Serine 181 (L-S-S(p)-S-P) derived from Human AMPK β1 |
抗原种属 | human |
Uniprot ID |
分子量 | Actual: 38 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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