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Anti-Phospho-AMPK β1 (Ser181) Polyclonal Antibody

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Anti-Phospho-AMPK β1 (Ser181) Polyclonal Antibody
产品编号 TMAC-00181
别名 p-AMPK β1 (Ser181), p-AMPK β1 (S181), AMPK β1 (p-Ser181), AMPK β1 (p-S181)

Anti-Phospho-AMPK β1 (Ser181) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-AMPK β1 (Ser181)。Anti-Phospho-AMPK β1 (Ser181) Polyclonal Antibody 可用于 WB。

Anti-Phospho-AMPK β1 (Ser181) Polyclonal Antibody

Anti-Phospho-AMPK β1 (Ser181) Polyclonal Antibody

Rating icon 还可以
Anti-Phospho-AMPK β1 (Ser181) Polyclonal Antibody
产品编号 TMAC-00181 别名 p-AMPK β1 (Ser181), p-AMPK β1 (S181), AMPK β1 (p-Ser181), AMPK β1 (p-S181)

Anti-Phospho-AMPK β1 (Ser181) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-AMPK β1 (Ser181)。Anti-Phospho-AMPK β1 (Ser181) Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,480
5日内发货
100 μL
¥ 2,245
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-AMPK β1 (Ser181) Polyclonal Antibody is a Rabbit antibody targeting Phospho-AMPK β1 (Ser181). Anti-Phospho-AMPK β1 (Ser181) Polyclonal Antibody can be used in WB.
别名p-AMPK β1 (Ser181), p-AMPK β1 (S181), AMPK β1 (p-Ser181), AMPK β1 (p-S181)
Ig Type
IgG
交叉反应
Human,Mouse,Rat
验证活性
1. Western blot analysis of extracts from Rat kindey using AMPK β1(Phospho-Ser181) Antibody TMAC-00181.The lane on the right is treated with the antigen-specific peptide.
应用
抗体种类
Polyclonal
宿主来源Rabbit
构建方式Polyclonal Antibody
纯化方式Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
性状Liquid
缓冲液Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
研究背景Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).
偶联与修饰
偶联
Unconjugated
其他可选修饰符
Phospho
抗原信息
免疫原
Peptide sequence around phosphorylation site of Serine 181 (L-S-S(p)-S-P) derived from Human AMPK β1
抗原种属
human
Uniprot ID
化学信息
分子量Actual: 38 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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