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Deltamethrin

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纯度: 99.85%

货号 T20754Cas号 52918-63-5

别名 溴氰菊酯, RU-22974, RU 22974, K-Othrin, Esbecythrin, Decamethrin, Butoss

Deltamethrin (RU 22974) 是一种具有神经毒性的拟除虫菊酯杀虫剂,在大鼠中能够产生一系列可逆的运动症状(如包括后肢僵硬、舞蹈性关节炎)。

Deltamethrin
其他形式的 “Deltamethrin”:
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Deltamethrin

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Rating icon 很棒

纯度: 99.85%

货号 T20754 别名 溴氰菊酯, RU-22974, RU 22974, K-Othrin, Esbecythrin, Decamethrin, ButossCas号 52918-63-5

Deltamethrin (RU 22974) 是一种具有神经毒性的拟除虫菊酯杀虫剂,在大鼠中能够产生一系列可逆的运动症状(如包括后肢僵硬、舞蹈性关节炎)。

规格价格库存数量
10 mg
¥ 115
现货
25 mg
¥ 169
现货
50 mg
¥ 233
现货
100 mg
¥ 328
现货
200 mg
¥ 469
现货
500 mg
¥ 795
现货
1 g
¥ 1,170
现货
1 mL x 10 mM (in DMSO)
¥ 363
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产品介绍


Deltamethrin AI Summary
Deltamethrin displays a diverse array of bioactivities, indicating its potential for multiple therapeutic and pest control applications. It exhibits antagonistic activity against the interaction between CBF-beta and RUNX1, thyroid hormone receptor beta signaling, peroxisome proliferator-activated receptor gamma signaling, glucocorticoid receptor signaling, and retinoid X receptor alpha signaling. Conversely, it shows agonistic activity towards glucocorticoid receptor signaling, farnesoid X receptor signaling, and activating activity on nuclear factor-kappa B (NF-kB), antioxidant response element (ARE), and pregnane X receptor (both human and rat) signaling pathways. Additionally, Deltamethrin inhibits the binding or entry of Lassa and Marburg viruses into cells. In terms of insecticidal properties, Deltamethrin is effective against various insect species, including second-instar larvae of Plutella xylostella, Culex pipiens pallens larvae, and adult Doru luteipes, with demonstrated efficacy at low concentrations. It also exhibits strong insecticidal activity against Mythimna separata and second-instar Spodoptera frugiperda, with potent toxic effects and high selectivity ratios for targeted pests. Furthermore, it is effective against Helicoverpa armigera with varying LD50 values and resistance factors, Bemisia tabaci with cross-resistance observed, Bactrocera oleae, Drosophila melanogaster, Nilaparvata lugens affecting multiple life cycle aspects, and Aedes aegypti mosquitoes displaying significant larvicidal activity. The compound's broad-spectrum bioactivities suggest its utility in therapeutic interventions for diseases such as acute myeloid leukemia, viral infections, and various insect-related plant and public health issues..
Note: Summary generated by AI. Data source: ChEMBL
生物活性
产品描述
Deltamethrin (RU 22974), a neurotoxic pyrethroid insecticide, produces a reversible sequence of motor symptoms in rats involving hind limb rigidity and choreoathetosis.Deltamethrin is globally used in crop protection, control of malaria and other vector-borne diseases. It is easily degradable.
别名溴氰菊酯, RU-22974, RU 22974, K-Othrin, Esbecythrin, Decamethrin, Butoss
化学信息
分子量505.20
分子式C22H19Br2NO3
CAS No.52918-63-5
SmilesCC1(C)C(\C=C(/Br)Br)C1C(=O)OC(C#N)C1=CC=CC(OC2=CC=CC=C2)=C1
密度1.5214 g/cm3 (Estimated)
颜色White
物理性状Solid
储存&溶解度
存储keep away from direct sunlight,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
溶解度信息
DMSO: 250 mg/mL (494.85 mM), Sonication is recommended.
体内实验配方
10% DMSO+90% Corn Oil: 2.5 mg/mL (4.95 mM), Sonication is recommeded.
请按顺序添加溶剂,在添加下一种溶剂之前,尽可能使溶液澄清。如有必要,可通过加热、超声、涡旋处理进行溶解。工作液建议现配现用。以上配方仅供参考,体内配方并不是绝对的,请根据不同情况进行调整。
溶液配制表
DMSO
1mg5mg10mg50mg
1 mM1.9794 mL9.8971 mL19.7941 mL98.9707 mL
5 mM0.3959 mL1.9794 mL3.9588 mL19.7941 mL
10 mM0.1979 mL0.9897 mL1.9794 mL9.8971 mL
20 mM0.0990 mL0.4949 mL0.9897 mL4.9485 mL
50 mM0.0396 mL0.1979 mL0.3959 mL1.9794 mL
100 mM0.0198 mL0.0990 mL0.1979 mL0.9897 mL

计算器

  • 摩尔浓度 计算器
  • 稀释 计算器
  • 配液 计算器
  • 分子量 计算器

体内实验配液计算器

请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法:
TargetMol | Animal experiments 比如您的给药剂量是10 mg/kg,每只动物体重20g,给药体积100 μLTargetMol | Animal experiments 一共给药动物10只,您使用的配方为5%TargetMol | reagent DMSO + 30%PEG300 + 5%Tween 80 + 60%Saline/PBS/ddH2O, 那么您的工作液浓度为2mg/mL
母液配置方法: 2 mg 药物溶于 50 μLDMSOTargetMol | reagent ( 母液浓度为 40 mg/mL ), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:50μLDMSOTargetMol | reagent 母液,添加 300 μLPEG300TargetMol | reagent 混匀澄清,再加 50μLTween80, 混匀澄清,再加 600μLSaline/PBS/ddH2OTargetMol | reagent 混匀澄清

以上为“体内实验配液计算器”的使用方法举例,并不是具体某个化合物的推荐配制方式,请根据您的实验动物和给药方式选择适当的溶解方案。

方案所需的各类助溶剂如: DMSOPEG300 / PEG400Tween 80SBE-β-CD玉米油 等, 均可在TargetMol网站点击购买。
1 请输入动物实验的基本信息
mg/kg
g
μL
2 请输入动物体内配方组成,不同的产品配方组成不同,如有配方需求,可先联系我们提供正确的体内配方。
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

剂量转换

对于不同动物的给药剂量换算,您也可以参考 更多

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