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Anti-PHEX Polyclonal Antibody

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货号 TMAB-10265

Anti-PHEX Polyclonal Antibody 是一种 Rabbit 抗体,靶向 PHEX。Anti-PHEX Polyclonal Antibody 可用于 FCM。

Anti-PHEX Polyclonal Antibody

Anti-PHEX Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-10265

Anti-PHEX Polyclonal Antibody 是一种 Rabbit 抗体,靶向 PHEX。Anti-PHEX Polyclonal Antibody 可用于 FCM。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍


生物活性
产品描述
Anti-PHEX Polyclonal Antibody is a Rabbit antibody targeting PHEX. Anti-PHEX Polyclonal Antibody can be used in FCM.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,Sheep)
应用FCM
推荐剂量
FCM: 1μg/Test
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Membrane.
组织特异性Lymphocytes and fetal brain; not in adult brain, placenta, skeletal muscle and pancreas; not in adult and fetal heart, lung, liver and kidney.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The PHEX a 749 amino acid protein that putatively consists of an intracellular, transmembrane and extracellular domain. PHEX mutations have been observed in 60-80% of hypophosphatemic rickets patients. The PHEX protein, which is a single-pass membrane protein, is also designated HYP, X-linked hypophosphatemia protein or metalloendopeptidase homolog PEX. PHEX plays an active role in bone and dentin mineralization and renal phosphate re-absorption. X-linked hypophosphatemic rickets, also designated HYP, is an X-linked dominant disorder characterized by impaired phosphate uptake in the kidney, which is likely to be caused by abnormal regulation of sodium phosphate cotransport in the proximal tubules. Clinical manifestations include skeletal deformities, growth failure, craniosynostosis, paravertebral calcifications, pseudofractures in lower extremities, and muscular hypotonia with onset in early childhood.
抗原信息
免疫原
KLH conjugated synthetic peptide: Human PHEX
抗原种属
Human
基因名称
PHEX
基因ID
蛋白名称
Phosphate-regulating neutral endopeptidase PHEX
Uniprot ID
功能
Probably involved in bone and dentin mineralization and renal phosphate reabsorption.
化学信息
分子量Theoretical: 86 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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