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Anti-Marapsin Antibody (8L443)
还可以产品编号 TMAY-02243
Anti-Marapsin Antibody (8L443) 是一种 Rabbit 抗体，靶向 Marapsin。Anti-Marapsin Antibody (8L443) 可用于 WB,IP。
Anti-Marapsin Antibody (8L443)
Anti-Marapsin Antibody (8L443)
还可以产品编号 TMAY-02243
Anti-Marapsin Antibody (8L443) 是一种 Rabbit 抗体，靶向 Marapsin。Anti-Marapsin Antibody (8L443) 可用于 WB,IP。
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产品介绍
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偶联与修饰
抗原信息
| 产品描述 | Anti-Marapsin Antibody (8L443) is a Rabbit antibody targeting Marapsin. Anti-Marapsin Antibody (8L443) can be used in WB,IP. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 8L443 |
| 交叉反应 | Human |
| 验证活性 | 1. Anti-PRSS27 rabbit monoclonal antibody at 1:500 dilution. -Lane A: K562 Whole Cell lysate. -Lysates/proteins at 30 μg per lane. -Secondary -Goat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution. -Developed using the Odyssey technique. -Performed under reducing conditions. -Predicted band size:32 kDa. -Observed band size:32 kDa. 2. PRSS27 was immunoprecipitated using: -Lane A:0.5 mg K562 Whole Cell Lysate. -2 µL anti-PRSS27 rabbit monoclonal antibody and 15 μl of 50 % Protein G agarose. -Primary antibody: -Anti-PRSS27 rabbit monoclonal antibody, at 1:200 dilution. -Secondary antibody: -Dylight 800-labeled antibody to rabbit IgG (H+L), at 1:5000 dilution. -Developed using the odyssey technique. -Performed under reducing conditions. -Predicted band size: 32 kDa. -Observed band size: 32 kDa |
| 应用 | WB,IP |
| 推荐剂量 | WB: 1:500-1:2000; IP: 4-6 μL/mg of lysate |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human Pancreasin / Marapsin / PRSS27 (rh Pancreasin / Marapsin / PRSS27; TMPY-02117; Q9BQR3; Met1-Lys290). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | The name "Pancreasin" because it is transcribed strongly in the pancreas. This secreted, tryptic serine protease, also known as Marapsin or PRSS27 (Protease, serine, 27), is a member of the peptidase S1 family. Pancreasin is inhibited by benzamidine and leupeptin but resists several classic inhibitors of trypsin. Marapsin was constitutively expressed in nonkeratinizing stratified squamous epithelia of human esophagus, tonsil, cervix, larynx, and cornea. In fact, marapsin was the second most strongly up-regulated protease in psoriatic lesions, where expression was localized to the upper region of the hyperplastic epidermis. Similarly, in the hyperproliferative epithelium of regenerating murine skin wounds, marapsin localized to the suprabasal layers, where keratinocytes undergo squamous differentiation. Marapsin's restricted expression, localization, and cytokine-inducible expression suggest a role in the terminal differentiation of keratinocytes in hyperproliferating squamous epithelia. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human Pancreasin / Marapsin / PRSS27 protein (TMPY-02117) |
| 抗原种属 | Human |
| 研究领域 | Serine Proteases and Regulators |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
SCI 文献
计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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