Anti-GBA Antibody (7E768)

Name: Anti-GBA Antibody (7E768)
Brand: TargetMol
SKU: TMAH-00476
Rating: 4.5 (1 reviews)

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产品编号 TMAH-00476

Anti-GBA Antibody (7E768) 是一种抗体，靶向 GBA。Anti-GBA Antibody (7E768) 可用于 ELISA, WB。

Anti-GBA Antibody (7E768)

还可以

产品编号 TMAH-00476

Anti-GBA Antibody (7E768) 是一种抗体，靶向 GBA。Anti-GBA Antibody (7E768) 可用于 ELISA, WB。

规格	价格	库存	数量
50 μL	¥ 1,310	5日内发货
100 μL	¥ 2,180	5日内发货

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产品描述	Anti-GBA Antibody (7E768) is an antibody targeting GBA. Anti-GBA Antibody (7E768) can be used in ELISA, WB.
Ig Type	Rabbit IgG
克隆号	7E768
交叉反应	Human
验证活性	Western Blot -Positive WB detected in: Hela whole cell lysate, MCF-7 whole cell lysate, 293T whole cell lysate, U87 whole cell lysate -All lanes: GBA antibody at 1:2000 -Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution -Predicted band size: 60, 58, 55, 51, 30 kDa -Observed band size: 60 kDa
应用	ELISA, WB
推荐剂量	WB:1:500-1:5000.
抗体种类	Monoclonal
亚细胞定位	Lysosome membrane; Peripheral membrane protein; Lumenal side.
构建方式	Recombinant Antibody
纯化方式	Affinity-chromatography
性状	Liquid
缓冲液	Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
研究背景	Glucosylceramidase that catalyzes, within the lysosomal compartment, the hydrolysis of glucosylceramide/GlcCer into free ceramide and glucose. Thereby, plays a central role in the degradation of complex lipids and the turnover of cellular membranes. Through the production of ceramides, participates in the PKC-activated salvage pathway of ceramide formation. Also plays a role in cholesterol metabolism. May either catalyze the glucosylation of cholesterol, through a transglucosylation reaction that transfers glucose from glucosylceramide to cholesterol. The short chain saturated C8:0-GlcCer and the mono-unsaturated C18:0-GlcCer being the most effective glucose donors for that transglucosylation reaction. Under specific conditions, may alternatively catalyze the reverse reaction, transferring glucose from cholesteryl-beta-D-glucoside to ceramide. Finally, may also hydrolyze cholesteryl-beta-D-glucoside to produce D-glucose and cholesterol.