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Anti-Phospho-HCLS1 (Tyr378) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-HCLS1 (Tyr378)。Anti-Phospho-HCLS1 (Tyr378) Polyclonal Antibody 可用于 WB,ELISA。
Anti-Phospho-HCLS1 (Tyr378) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-HCLS1 (Tyr378)。Anti-Phospho-HCLS1 (Tyr378) Polyclonal Antibody 可用于 WB,ELISA。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,490 | 5日内发货 | |
100 μL | ¥ 2,240 | 5日内发货 |
产品描述 | Anti-Phospho-HCLS1 (Tyr378) Polyclonal Antibody is a Rabbit antibody targeting Phospho-HCLS1 (Tyr378). Anti-Phospho-HCLS1 (Tyr378) Polyclonal Antibody can be used in WB,ELISA. |
别名 | p-HCLS1 (Y378), p-HCLS1 (Tyr378), HCLS1 (p-Y378), HCLS1 (p-Tyr378) |
Ig Type | IgG |
交叉反应 | Human |
应用 | |
推荐剂量 | WB: 1:500-2000; ELISA: 1:40000 |
抗体种类 | Polyclonal |
宿主来源 | Rabbit |
构建方式 | Polyclonal Antibody |
纯化方式 | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
性状 | Liquid |
缓冲液 | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
研究背景 | developmental stage:Expressed in early stage of myeloid and erythroid differentiation.,function:Substrate of the antigen receptor-coupled tyrosine kinase. Plays a role in antigen receptor signaling for both clonal expansion and deletion in lymphoid cells. May also be involved in the regulation of gene expression.,PTM:Phosphorylated by LYN; rapidly after cross-linking of surface IgM on B-cells.,similarity:Contains 1 SH3 domain.,similarity:Contains 4 cortactin repeats.,subunit:Associates with the SH2 and SH3 domains of LCK. Binding to he LCK SH3 domain occurs constitutively, while binding to the LCK SH2 domain occurs only upon TCR stimulation. A similar binding pattern was observed with LYN, but not with FYN in which the FYN SH2 region associates upon TCR stimulation but the FYN SH3 region does not associate regardless of TCR stimulation. Directly associates with HAX1, through binding to its C-terminal region. Interacts with HS1BP3.,tissue specificity:Expressed only in tissues and cells of hematopoietic origin., |
偶联 | Unconjugated |
其他可选修饰符 | Phospho |
免疫原 | A synthesized phosphopeptide: human Lck BP-1 around the phosphorylation site of Tyr378 |
抗原种属 | human |
Uniprot ID |
分子量 | Actual: 78 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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