Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Enpp/Carbonic anhydrase-IN-2 is a potent dual inhibitor of Enpp and carbonic anhydrase, inhibiting NPP1, NPP2, NPP3, CA-IX, CA-XII, with IC50 values of 1.13, 1.07, 0.74, 0.33, 0.68, respectively.Enpp/Carbonic anhydrase-IN-2 induced apoptosis.Enpp/Carbonic anhydrase-IN-2 has antiproliferative activity against cancer cells and low cytotoxicity against normal cells.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
1 mg | ¥ 927 | 现货 | ||
5 mg | ¥ 2,320 | 现货 | ||
10 mg | ¥ 3,730 | 现货 | ||
25 mg | ¥ 5,910 | 现货 | ||
50 mg | ¥ 7,880 | 现货 | ||
100 mg | ¥ 10,800 | 现货 | ||
500 mg | ¥ 21,700 | 现货 | ||
1 mL * 10 mM (in DMSO) | ¥ 2,420 | 现货 |
产品描述 | Enpp/Carbonic anhydrase-IN-2 is a potent dual inhibitor of Enpp and carbonic anhydrase, inhibiting NPP1, NPP2, NPP3, CA-IX, CA-XII, with IC50 values of 1.13, 1.07, 0.74, 0.33, 0.68, respectively.Enpp/Carbonic anhydrase-IN-2 induced apoptosis.Enpp/Carbonic anhydrase-IN-2 has antiproliferative activity against cancer cells and low cytotoxicity against normal cells. |
靶点活性 | CA IX:0.33 μM, CA XII:0.68 μM, NPP1:1.13 μM, NPP2:1.07 μM, NPP3:0.74 μM |
分子量 | 429.5 |
分子式 | C23H24FNO4S |
CAS No. | 2883495-39-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 42.95 mg/mL (100 mM), Sonication is recommended.
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
DMSO | 1 mM | 2.3283 mL | 11.6414 mL | 23.2829 mL | 58.2072 mL |
5 mM | 0.4657 mL | 2.3283 mL | 4.6566 mL | 11.6414 mL | |
10 mM | 0.2328 mL | 1.1641 mL | 2.3283 mL | 5.8207 mL | |
20 mM | 0.1164 mL | 0.5821 mL | 1.1641 mL | 2.9104 mL | |
50 mM | 0.0466 mL | 0.2328 mL | 0.4657 mL | 1.1641 mL | |
100 mM | 0.0233 mL | 0.1164 mL | 0.2328 mL | 0.5821 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
Enpp/Carbonic anhydrase-IN-2 2883495-39-2 Apoptosis Metabolism PDE Carbonic Anhydrase Enpp/Carbonic anhydraseIN2 Inhibitor inhibitor inhibit