Fas Ligand, also known as FASLG and CD95L, is the ligand for FAS. It is a transmembrane protein which binds to TNFRSF6/FAS. Interaction of FAS with fas Ligand is critical in triggering apoptosis of some types of cells such as lymphocytes. Fas Ligand may be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. Fas Ligand Protein, Mouse, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 18.2 kDa and the accession number is AAB02915.1.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
50 μg | ¥ 1,950 | 5日内发货 | ||
500 μg | ¥ 16,500 | 5日内发货 |
生物活性 | Testing in progress |
产品描述 | Fas Ligand, also known as FASLG and CD95L, is the ligand for FAS. It is a transmembrane protein which binds to TNFRSF6/FAS. Interaction of FAS with fas Ligand is critical in triggering apoptosis of some types of cells such as lymphocytes. Fas Ligand may be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. Fas Ligand Protein, Mouse, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 18.2 kDa and the accession number is AAB02915.1. |
种属 | Mouse |
表达系统 | P. pastoris (Yeast) |
标签 | N-His |
蛋白编号 | AAB02915.1 |
别名 | CD178, Apt1lg1, Fasl, Cd95l, Faslg, Tnfsf6, gld, Fas ligand, CD95-L, Fas-L |
蛋白构建 | Mouse Faslg (AAB02915.1) (Pro132-Leu279) |
蛋白纯度 | > 90 % as determined by SDS-PAGE. |
分子量 | 18.2 kDa (predicted) |
内毒素 | Please contact us for more information. |
缓冲液 | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization. |
复溶方法 | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
存储 |
It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted protein solutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
运输方式 |
In general, Lyophilized powders are shipping with blue ice. |
研究背景 | Fas Ligand, also known as FASLG and CD95L, is the ligand for FAS. It is a transmembrane protein which binds to TNFRSF6/FAS. Interaction of FAS with fas Ligand is critical in triggering apoptosis of some types of cells such as lymphocytes. Fas Ligand may be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. |
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Fas Ligand Protein, Mouse, Recombinant (His) CD178 Apt1lg1 Fasl Cd95l CD-178 Faslg Tnfsf6 gld Fas ligand CD 178 CD95-L Fas-L recombinant recombinant-proteins proteins protein