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Anti-Claudin-5 Antibody (7Z609) 是一种 Rabbit 抗体,靶向 Claudin-5。Anti-Claudin-5 Antibody (7Z609) 可用于 WB,IHC。
Anti-Claudin-5 Antibody (7Z609) 是一种 Rabbit 抗体,靶向 Claudin-5。Anti-Claudin-5 Antibody (7Z609) 可用于 WB,IHC。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,495 | 5日内发货 | |
100 μL | ¥ 2,490 | 5日内发货 |
产品描述 | Anti-Claudin-5 Antibody (7Z609) is a Rabbit antibody targeting Claudin-5. Anti-Claudin-5 Antibody (7Z609) can be used in WB,IHC. |
别名 | Transmembrane protein deleted in VCFS, TMDVCF, CLDN5, Claudin5, AWAL TMVCF |
Ig Type | IgG |
克隆号 | 7Z609 |
交叉反应 | Human |
验证活性 | 1. Western blot analysis of Claudin 5 on human lung cells lysates using anti-Claudin 5 antibody at 1/500 dilution. 2. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-Claudin 5 antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-Claudin 5 antibody. Counter stained with hematoxylin. 4. Immunohistochemical analysis of paraffin-embedded human lung tissue using anti-Claudin 5 antibody. Counter stained with hematoxylin. 5. Immunohistochemical analysis of paraffin-embedded human uterus tissue using anti-Claudin 5 antibody. Counter stained with hematoxylin. |
应用 | |
推荐剂量 | WB: 1:2000-5000; IHC: 1:50-200 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | Recombinant Antibody |
纯化方式 | ProA affinity purified |
性状 | Liquid |
缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
研究背景 | The claudin superfamily consists of many structurally related proteins in humans. These proteins are important structural and functional components of tight junctions in paracellular transport. Claudins are located in both epithelial and endothelial cells in all tight junction-bearing tissues. Three classes of proteins are known to localize to tight junctions, including the claudins, Occludin and Junction adhesion molecule. Claudins, which consist of four transmembrane domains and two extracellular loops make up tight junction strands. Claudin expression is highly restricted to specfic regions of different tissues and may have an important role in transcellular transport through tight junctions. Claudin-5 is expressed in the endothelial junctions of the rat liver and in junctions of acinar cells of the pancreas. Human Claudin-5 is abundantly expressed in adult lung, heart and skeletal muscle and is deleted in patients with velocardiofacial syndrone, which is characterized by cleft palate, facial dysmorphology and conotruncal heart defects. |
偶联 | Unconjugated |
免疫原 | Recombinant Protein |
Uniprot ID |
分子量 | Theoretical: 24 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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