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Anti-ASPSCR1 Polyclonal Antibody

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货号 TMAB-02879

Anti-ASPSCR1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 ASPSCR1。Anti-ASPSCR1 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-ASPSCR1 Polyclonal Antibody

Anti-ASPSCR1 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-02879

Anti-ASPSCR1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 ASPSCR1。Anti-ASPSCR1 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍


生物活性
产品描述
Anti-ASPSCR1 Polyclonal Antibody is a Rabbit antibody targeting ASPSCR1. Anti-ASPSCR1 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human,Mouse,Rat
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Endomembrane system; Peripheral membrane protein.
组织特异性Ubiquitous. Highly expressed in testis, heart, skeletal muscle and pancreas.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Glut4 is a twelve pass transmembrane protein (12TM) whose carboxy-terminus may dictate its cellular localization. Aberrant Glut4 expression has been suggested to contribute to such maladies as obesity and diabetes. Glut4 null mice have shown that while functional Glut4 protein is not required for maintaining normal glucose levels, it is necessary for sustained growth, normal cellular glucose, fat metabolism and prolonged longevity. TUG (ASPL in humans) regulates the trafficking of glucose via Glut4. Full-length TUG forms a complex with Glut4 and in 3T3-L1 adipocytes and this complex is present in unstimulated cells and is disassembled by insulin. TUG acts by trapping endocytosed Glut4 and tethering it intracellularly. Insulin mobilizes this pool of retained Glut4 by releasing the tether.
抗原信息
免疫原
KLH conjugated synthetic peptide: human TUG/ASPC
抗原种属
Human
基因名称
ASPSCR1
基因ID
蛋白名称
Tether containing UBX domain for GLUT4
Uniprot ID
功能
Tethering protein that sequesters GLUT4-containing vesicles in the cytoplasm in the absence of insulin. Modulates the amount of GLUT4 that is available at the cell surface.
化学信息
分子量Theoretical: 60 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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