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Anti-TBR1 Antibody (1Z281)

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Anti-TBR1 Antibody (1Z281)
产品编号 TMAC-03993
别名 TES-56, TES 56, T-brain-1, TBR 1, T-box brain protein 1, T brain 1 protein, T box brain protein 1, T box brain 1

Anti-TBR1 Antibody (1Z281) 是一种 Rabbit 抗体,靶向 TBR1。Anti-TBR1 Antibody (1Z281) 可用于 WB,IHC,FCM。

Anti-TBR1 Antibody (1Z281)

Anti-TBR1 Antibody (1Z281)

Rating icon 还可以
Anti-TBR1 Antibody (1Z281)
产品编号 TMAC-03993 别名 TES-56, TES 56, T-brain-1, TBR 1, T-box brain protein 1, T brain 1 protein, T box brain protein 1, T box brain 1

Anti-TBR1 Antibody (1Z281) 是一种 Rabbit 抗体,靶向 TBR1。Anti-TBR1 Antibody (1Z281) 可用于 WB,IHC,FCM。

规格价格库存数量
50 μL
¥ 1,480
5日内发货
100 μL
¥ 2,480
5日内发货
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产品介绍

生物活性
产品描述
Anti-TBR1 Antibody (1Z281) is a Rabbit antibody targeting TBR1. Anti-TBR1 Antibody (1Z281) can be used in WB,IHC,FCM.
别名TES-56, TES 56, T-brain-1, TBR 1, T-box brain protein 1, T brain 1 protein, T box brain protein 1, T box brain 1
Ig Type
IgG
交叉反应
Human,Mouse,Rat
验证活性
1. Immunohistochemical analysis of paraffin-embedded rat brain tissue using anti-TBR1 antibody. Counter stained with hematoxylin.
2. Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-TBR1 antibody. Counter stained with hematoxylin.
3. Flow cytometric analysis of SH-SY-5Y cells with TBR1 antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.
应用
推荐剂量
WB: 1:500-1000; IHC: 1:50-200; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景A novel murine and human gene, TBR-1, encodes a putative transcription factor related to the Brachyrury (T) gene that is expressed only in postmitotic cells. T-brain-1 (TBR-1) mRNA is largely restricted to the cerebral cortex, where, during embryogenesis, it defines different regions that give rise to the palecortex, limbic cortex and neocortex. TBR-1, Pax-6 and Emx-1 are expressed in the mouse and chicken pallium. The pallio-subpallial boundary lies at the interface between the TBR-1 and Dlx-2 expression domains. Chicken genes homolgous to these mouse genes are expressed in topologically comparable patterns during development, suggesting that mouse and chicken may have similar histogenetic specification processes and field homologies. CASK/LIN-2, a membrane-associated guanylate kinase, is required for EGFR localization and signaling. In adult rat brain, CASK is concentrated at neuronal synapses and binds to the cell-surface proteins. CASK can interact with TBR-1, which is involved in forebrain development. CASK enters into the nucleus and binds to a specific DNA sequence (the T-element) in a complex with TBR-1. Thus, CASK acts as a coactivator of TBR-1 to induce transcription of T-element containing genes, including reelin.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
化学信息
分子量Theoretical: 74 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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