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Anti-CYP2R1 Polyclonal Antibody

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货号 TMAB-04891

Anti-CYP2R1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 CYP2R1。Anti-CYP2R1 Polyclonal Antibody 可用于 WB,FCM。

Anti-CYP2R1 Polyclonal Antibody

Anti-CYP2R1 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-04891

Anti-CYP2R1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 CYP2R1。Anti-CYP2R1 Polyclonal Antibody 可用于 WB,FCM。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍


生物活性
产品描述
Anti-CYP2R1 Polyclonal Antibody is a Rabbit antibody targeting CYP2R1. Anti-CYP2R1 Polyclonal Antibody can be used in WB,FCM.
Ig Type
IgG
反应种属
Human,Mouse (predicted:Rat,Dog,Pig,Horse,Rabbit)
应用WBFCM
推荐剂量
WB: 1:500-2000; FCM: 2μg/Test
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
组织特异性Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景CYP2R1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are mono-oxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme is a microsomal vitamin D hydroxylase that converts vitamin D into the active ligand for the vitamin D receptor. Defects in CYP2R1 are a cause of 25-hydroxyvitamin D(3) deficiency, also known as pseudovitamin D(3) deficiency rickets due to 25-hydroxylase deficiency. First described in patients who had rickets at a young age despite a history of adequate vitamin D intake. The patients sera had low calcium concentrations, low phosphate concentrations, elevated alkaline phosphatase activity and low levels of 25-hydroxyvitamin D.
抗原信息
免疫原
KLH conjugated synthetic peptide: human CYP2R1
抗原种属
Human
基因名称
CYP2R1
基因ID
蛋白名称
Vitamin D 25-hydroxylase
Uniprot ID
化学信息
分子量Theoretical: 55 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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