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Anti-IRF2 Antibody (8B64)
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产品编号 TMAC-02216
别名 IRF2_HUMAN, IRF 2, Interferon regulatory factor 2, DKFZp686F0244
Anti-IRF2 Antibody (8B64) 是一种 Rabbit 抗体，靶向 IRF2。Anti-IRF2 Antibody (8B64) 可用于 WB,ICC/IF。
Anti-IRF2 Antibody (8B64)
Anti-IRF2 Antibody (8B64)
还可以产品编号 TMAC-02216 别名 IRF2_HUMAN, IRF 2, Interferon regulatory factor 2, DKFZp686F0244
Anti-IRF2 Antibody (8B64) 是一种 Rabbit 抗体，靶向 IRF2。Anti-IRF2 Antibody (8B64) 可用于 WB,ICC/IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,480 | 5日内发货 | |
| 100 μL | ¥ 2,495 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
化学信息
| 产品描述 | Anti-IRF2 Antibody (8B64) is a Rabbit antibody targeting IRF2. Anti-IRF2 Antibody (8B64) can be used in WB,ICC/IF. |
| 别名 | IRF2_HUMAN, IRF 2, Interferon regulatory factor 2, DKFZp686F0244 |
| Ig Type | IgG |
| 交叉反应 | Human,Mouse |
| 验证活性 | 1. Western blot analysis of IRF2 on human lung lysates using anti-IRF2 antibody at 1/1,000 dilution. 2. ICC staining IRF2 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 3. ICC staining IRF2 in A549 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 4. ICC staining IRF2 in PANC-1 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. |
| 应用 | |
| 推荐剂量 | WB: 1:1000-2000; ICC/IF: 1:50-200 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | ProA affinity purified |
| 性状 | Liquid |
| 缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| 研究背景 | Interferon regulatory factor-1 (IRF-1) and IRF-2 have been identified as novel DNA-binding factors that function as regulators of both type I interferon (interferon-α and β) and interferon-inducible genes. The two factors are structurally related, particularly in their N-terminal regions, which confer DNA binding specificity. In addition, both bind to the same sequence within the promoters of interferon-α and interferon-β genes. IRF-1 functions as an activator of interferon transcription, while IRF-2 binds to the same cis elements and represses IRF-1 action. IRF-1 and IRF-2 have been reported to act in a mutually antagonistic manner in regulating cell growth; overexpression of the repressor IRF-2 leads to cell transformation while concomitant overexpression of IRF-1 causes reversion. IRF-1 and IRF-2 are members of a larger family of DNA binding proteins that includes IRF-3, IRF-4, IRF-5, IRF-6, IRF-7, ISGF-3? p48 (a component of the ISGF-3 complex) and IFN consensus sequence-binding protein (ICSBP). |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein |
| Uniprot ID |
| 分子量 | Theoretical: 50 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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