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顶部生物活性储存和溶解信息计算器

Anti-TCN2 Antibody (8U681)

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产品编号 TMAY-03406

别名 transcobalamin II, Tcn-2, AW208754

Anti-TCN2 Antibody (8U681) 是一种 Rabbit 抗体，靶向 TCN2。Anti-TCN2 Antibody (8U681) 可用于 ELISA。

Anti-TCN2 Antibody (8U681)

Anti-TCN2 Antibody (8U681)

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产品编号 TMAY-03406 别名 transcobalamin II, Tcn-2, AW208754

Anti-TCN2 Antibody (8U681) 是一种 Rabbit 抗体，靶向 TCN2。Anti-TCN2 Antibody (8U681) 可用于 ELISA。

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100 μL
¥ 2,294
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产品介绍

生物活性
产品描述
Anti-TCN2 Antibody (8U681) is a Rabbit antibody targeting TCN2. Anti-TCN2 Antibody (8U681) can be used in ELISA.
别名transcobalamin II, Tcn-2, AW208754
Ig Type
Rabbit IgG
克隆号
8U681
交叉反应
Mouse
特异性
Mouse Transcobalamin II
应用ELISA
推荐剂量
ELISA: 1:5000-1:10000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Mouse TCN2 (rM TCN2; TMPY-02192; O88968; Met1-Trp430).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Transcobalamin II, also known as TCN2 and TC II, is a plasma protein that binds cobalamin (Cbl; vitamin B12) as it is absorbed in the terminal ileum and distributes to tissues. The circulating transcobalamin II-cobalamin complex binds to receptors on the plasma membrane of tissue cells and is then internalized by receptor-mediated endocytosis. Transcobalamin II is a non-glycolated secretory protein of molecular mass 43 kDa. Its plasma membrane receptor (TC II-R) is a heavily glycosylated protein with a monomeric molecular mass of 62 kDa. Human TCN2 gene is composed of nine exons and eight introns spanning approximately 2 kb with multiple potential transcription start sites. A number of genetic abnormalities are characterized either by a failure to express TCN2 or by synthesis of an abnormal protein. The TCN2 deficiency results in cellular cobalamin deficiency, an early onset of megaloblastic anaemia, and neurological abnormalities.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Mouse TCN2 protein (TMPY-02192)
抗原种属
Mouse
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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关键词

AW-208754AW 208754

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