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Anti-TCN2 Antibody (8U681) 是一种 Rabbit 抗体,靶向 TCN2。Anti-TCN2 Antibody (8U681) 可用于 ELISA。
Anti-TCN2 Antibody (8U681) 是一种 Rabbit 抗体,靶向 TCN2。Anti-TCN2 Antibody (8U681) 可用于 ELISA。
产品描述 | Anti-TCN2 Antibody (8U681) is a Rabbit antibody targeting TCN2. Anti-TCN2 Antibody (8U681) can be used in ELISA. |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 8U681 |
交叉反应 | Mouse |
应用 | ELISA |
推荐剂量 | ELISA: 1:5000-1:10000 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse TCN2 (rM TCN2; TMPY-02192; O88968; Met1-Trp430). |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | Transcobalamin II, also known as TCN2 and TC II, is a plasma protein that binds cobalamin (Cbl; vitamin B12) as it is absorbed in the terminal ileum and distributes to tissues. The circulating transcobalamin II-cobalamin complex binds to receptors on the plasma membrane of tissue cells and is then internalized by receptor-mediated endocytosis. Transcobalamin II is a non-glycolated secretory protein of molecular mass 43 kDa. Its plasma membrane receptor (TC II-R) is a heavily glycosylated protein with a monomeric molecular mass of 62 kDa. Human TCN2 gene is composed of nine exons and eight introns spanning approximately 2 kb with multiple potential transcription start sites. A number of genetic abnormalities are characterized either by a failure to express TCN2 or by synthesis of an abnormal protein. The TCN2 deficiency results in cellular cobalamin deficiency, an early onset of megaloblastic anaemia, and neurological abnormalities. |
偶联 | Unconjugated |
免疫原 | Recombinant Mouse TCN2 protein (TMPY-02192) |
抗原种属 | Mouse |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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