β-Anomer

Name: β-Anomer
Brand: TargetMol
SKU: TNU0422
Price: 153 CNY
Availability: InStock
Rating: 5 (10 reviews)

一键复制产品信息

很棒

纯度: 99.81%

货号 TNU0422Cas号 356782-84-8

β-Anomer 具有抗病毒特性。

β-Anomer

一键复制产品信息

很棒

纯度: 99.81%

货号 TNU0422Cas号 356782-84-8

β-Anomer 具有抗病毒特性。

规格	价格	库存
10 mg	¥ 153	现货
25 mg	¥ 265	现货
50 mg	¥ 395	现货

库存状态实时更新，以官网显示为准，现货产品可直接加购物车下单

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纯度: 99.81%

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COA HNMR HPLC 产品操作手册

产品介绍

β-Anomer AI Summary

β-Anomer exhibits significant antiviral activity against Yellow Fever Virus (YFV) and Influenza viruses A and B. In Syrian golden hamsters infected with YFV, the compound effectively reduces serum alanine aminotransferase levels, delays mortality, and decreases viral titers in the liver, particularly when administered at higher dosages. However, it shows limited efficacy in inhibiting cytopathic effects in African green monkey Vero cells infected with YFV, with EC50 values ranging from 1,080,000 nM to 2,630,000 nM, and has a Selectivity Index above 3.6. Against Influenza virus strains in MDCK cells, β-Anomer significantly reduces viral replication, demonstrating higher potency against the Influenza B strain with EC50 values between 19,000 nM and 24,000 nM. The compound's cytotoxic effects are low, with CC50 values exceeding 250,000 nM. β-Anomer does not exhibit antifungal or antibacterial activity against a variety of pathogens, including Candida albicans, Cryptococcus neoformans, and several bacterial strains such as Escherichia coli and Staphylococcus aureus. It also does not cause hemolysis of human red blood cells, and it shows low cytotoxicity against HEK293 cells. Overall, β-Anomer shows promise as an antiviral agent, particularly in animal models, but further studies are needed to fully understand its efficacy and safety profiles..

Note: Summary generated by AI. Data source: ChEMBL

生物活性

产品描述	β-Anomer shows antiviral properties.

化学信息

分子量	271.23
分子式	C₁₀H₁₃N₃O₆
CAS No.	356782-84-8
Smiles	O[C@H]1[C@@H](O[C@H](CO)[C@H]1O)N2C(=O)C(C(N)=O)=NC=C2

储存&溶解度

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

DMSO: 50 mg/mL (184.35 mM), Sonication is recommended.

溶液配制表

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.6869 mL	18.4345 mL	36.8691 mL	184.3454 mL
5 mM	0.7374 mL	3.6869 mL	7.3738 mL	36.8691 mL
10 mM	0.3687 mL	1.8435 mL	3.6869 mL	18.4345 mL
20 mM	0.1843 mL	0.9217 mL	1.8435 mL	9.2173 mL
50 mM	0.0737 mL	0.3687 mL	0.7374 mL	3.6869 mL
100 mM	0.0369 mL	0.1843 mL	0.3687 mL	1.8435 mL