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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-DLL4 Polyclonal Antibody

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货号 TMAB-00554

别名 δ-like 4 (Drosophila), δ-like 4, hδ2, hdelta2, delta-like 4 (Drosophila), Delta-like 4

Anti-DLL4 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 DLL4。Anti-DLL4 Polyclonal Antibody 可用于 WB。

Anti-DLL4 Polyclonal Antibody

Anti-DLL4 Polyclonal Antibody

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货号 TMAB-00554 别名 δ-like 4 (Drosophila), δ-like 4, hδ2, hdelta2, delta-like 4 (Drosophila), Delta-like 4

Anti-DLL4 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 DLL4。Anti-DLL4 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-DLL4 Polyclonal Antibody is a Rabbit antibody targeting DLL4. Anti-DLL4 Polyclonal Antibody can be used in WB.
别名δ-like 4 (Drosophila), δ-like 4, hδ2, hdelta2, delta-like 4 (Drosophila), Delta-like 4
Ig Type
IgG
反应种属
Human,Rat (predicted:Mouse,Dog,Pig,Cow,Horse)
验证活性
1. Sample:
Lane 1: Human K562 cell Lysates
Lane 2: Human THP-1 cell Lysates
Lane 3: Human 293T cell Lysates
Primary: Anti-DLL4 (TMAB-00554) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 75 kDa
Observed band size: 75 kDa
2. Tissue/cell: mouse embryo tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer (0.01M, pH6.0), Boiling bathing for 15 min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30 min; Blocking buffer (normal goat serum) at 37°C for 20 min;
Incubation: Anti-Delta 4 Polyclonal Antibody, Unconjugated (TMAB-00554) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody and DAb staining.
verifiedActivityverifiedActivity
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Membrane; Single-pass type I membrane protein (Probable).
组织特异性Expressed in vascular endothelium.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1 mg/mL
研究背景The LIN-12/Notch family of transmembrane receptors is believed to play a central role in development by regulating cell fate decisions. Notch proteins have been found to be overexpressed or rearranged in human tumors. Ligands for Notch include Jagged, Jagged-2 and Delta. While blocking the differentiation of progenitor cells into the B-cell lineage, Delta promotes the emergence of a population of cells with T cell/NK-cell characteristics. The protein is a membrane protein expressed in heart, pancreas, brain and muscle during gastrulation and early organogenesis and in adult heart and lung. Delta-4 is a membrane protein that activates Notch-1 and Notch-4. It is expressed in a wide range of adult and fetal tissues, especially in vascular endothelium.
抗原信息
免疫原
KLH conjugated synthetic peptide: human DLL4
抗原种属
Human
基因名称
DLL4
基因ID
54567
蛋白名称
delta-like protein 4
Uniprot ID
Q9NR61
研究领域
Cell differentiation,Cell Differentiation,Notch Pathway
功能
Plays a role in the Notch signaling pathway. Activates Notch-1 and Notch-4.
化学信息
分子量Theoretical: 72 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | store at -20°C

计算器

  • 稀释 计算器

关键词

Δ-like 4Drosophila
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