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顶部生物活性储存和溶解信息计算器

Anti-Phospho-APP (Thr743, 668) Polyclonal Antibody

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Anti-Phospho-APP (Thr743, 668) Polyclonal Antibody
产品编号 TMAC-00190
别名 p-APP (Thr743, 668), p-APP (T743, 668), APP (p-Thr743, 668), APP (p-T743, 668)

Anti-Phospho-APP (Thr743, 668) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-APP (Thr743, 668)。Anti-Phospho-APP (Thr743, 668) Polyclonal Antibody 可用于 WB,IHC,IF。

Anti-Phospho-APP (Thr743, 668) Polyclonal Antibody

Anti-Phospho-APP (Thr743, 668) Polyclonal Antibody

Rating icon 还可以
Anti-Phospho-APP (Thr743, 668) Polyclonal Antibody
产品编号 TMAC-00190 别名 p-APP (Thr743, 668), p-APP (T743, 668), APP (p-Thr743, 668), APP (p-T743, 668)

Anti-Phospho-APP (Thr743, 668) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-APP (Thr743, 668)。Anti-Phospho-APP (Thr743, 668) Polyclonal Antibody 可用于 WB,IHC,IF。

规格价格库存数量
50 μL
¥ 1,490
5日内发货
100 μL
¥ 2,240
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-APP (Thr743, 668) Polyclonal Antibody is a Rabbit antibody targeting Phospho-APP (Thr743, 668). Anti-Phospho-APP (Thr743, 668) Polyclonal Antibody can be used in WB,IHC,IF.
别名p-APP (Thr743, 668), p-APP (T743, 668), APP (p-Thr743, 668), APP (p-T743, 668)
Ig Type
IgG
交叉反应
Human,Mouse,Rat
验证活性
1. Western blot analysis of extracts from cos-7 cells (Lane 2), using Amyloid β A4 (Phospho-Thr743/668) Antibody TMAC-00190. The lane on the left is treated with antigen-specific peptide.
2. Immunohistochemical analysis of paraffin-embedded human brain tissue using Amyloid β A4 (phospho-Thr743/668) antibody TMAC-00190 (left)or the same antibody preincubated with blocking peptide (right).
3. Immunofluorescence staining of methanol-fixed HeLa cells using Amyloid β A4 (phospho-Thr743/668) Antibody TMAC-00190.
应用
WB
IHC
IF
推荐剂量
WB: 1:500-1000; IHC: 1:50-100; IF: 1:100-200
抗体种类
Polyclonal
宿主来源Rabbit
构建方式Polyclonal Antibody
纯化方式Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
性状Liquid
缓冲液Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
研究背景Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions. Can promote transcription activation through binding to APBB1-KAT5 and inhibits Notch signaling through interaction with Numb. Couples to apoptosis-inducing pathways such as those mediated by G(O) and JIP. Inhibits G(o) alpha ATPase activity By similarity. Acts as a kinesin I membrane receptor, mediating the axonal transport of beta-secretase and presenilin 1.
偶联与修饰
偶联
Unconjugated
其他可选修饰符
Phospho
抗原信息
免疫原
Peptide sequence around phosphorylation site of threonine743 /668 (A-V-T(p)-P-E) derived from Human Amyloid β A4
抗原种属
human
Uniprot ID
P05067
化学信息
分子量Actual: 140 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

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关键词

pAPP (Thr743, 668)pAPP (T743, 668)APP (pThr743, 668)APP (pT743, 668)APP (phospho-Thr743, 668)APP (phospho-T743, 668)

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