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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-TSG101 Antibody (5J998)

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货号 TMAB-13861

Anti-TSG101 Antibody (5J998) 是一种 Mouse 抗体，靶向 TSG101。Anti-TSG101 Antibody (5J998) 可用于 WB。

Anti-TSG101 Antibody (5J998)

Anti-TSG101 Antibody (5J998)

一键复制产品信息
Rating icon 还可以
货号 TMAB-13861

Anti-TSG101 Antibody (5J998) 是一种 Mouse 抗体，靶向 TSG101。Anti-TSG101 Antibody (5J998) 可用于 WB。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,975
5日内发货
库存状态实时更新，以官网显示为准，现货产品可直接加购物车下单
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产品介绍

生物活性
产品描述
Anti-TSG101 Antibody (5J998) is a Mouse antibody targeting TSG101. Anti-TSG101 Antibody (5J998) can be used in WB.
Ig Type
IgG1, k
克隆号
5J998
反应种属
Human
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Monoclonal
宿主来源Mouse
亚细胞定位Cytoplasm. Membrane; Peripheral membrane protein. Nucleus. Late endosome membrane; Peripheral membrane protein. Note=Mainly cytoplasmic. Membrane-associated when active and soluble when inactive. Depending on the stage of the cell cycle, detected in the nucleus. Colocalized with CEP55 in the midbody during cytokinesis.
组织特异性Heart, brain, placenta, lung, liver, skeletal, kidney and pancreas.
构建方式Hybridoma Monoclonal Antibody
纯化方式Protein G purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression. [provided by RefSeq, Jul 2008]
抗原信息
免疫原
Recombinant Protein: human TSG101
抗原种属
Human
基因名称
Tsg101
基因ID
7251
蛋白名称
Tumor susceptibility gene 101 protein
Uniprot ID
Q99816
功能
Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Mediates the association between the ESCRT-0 and ESCRT-I complex. Required for completion of cytokinesis; the function requires CEP55. May be involved in cell growth and differentiation. Acts as a negative growth regulator. Involved in the budding of many viruses through an interaction with viral proteins that contain a late-budding motif P-[ST]-A-P. This interaction is essential for viral particle budding of numerous retroviruses.
化学信息
分子量Theoretical: 44 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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