ACVR2B Protein, Human/Cynomolgus, Recombinant (hFc)

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SPR兼容缓冲液

产品编号 TMPY-03925

ACVR2B Protein, Human/Cynomolgus, Recombinant (hFc) is expressed in HEK293 Cells. The accession number is Q13705-1(Human)/XP_045242398.1(Cynomolgus).

ACVR2B Protein, Human/Cynomolgus, Recombinant (hFc)

一键复制产品信息

SPR兼容缓冲液

产品编号 TMPY-03925

ACVR2B Protein, Human/Cynomolgus, Recombinant (hFc) is expressed in HEK293 Cells. The accession number is Q13705-1(Human)/XP_045242398.1(Cynomolgus).

规格	价格	库存
5 μg	¥ 385	6-8日内发货
10 μg	¥ 623	6-8日内发货
20 μg	¥ 987	5日内发货
50 μg	¥ 1,980	5日内发货
100 μg	¥ 3,380	5日内发货
200 μg	¥ 6,670	5日内发货

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产品信息

生物活性	Immobilized Human Activin A, No Tag at 1μg/ml (100μl/well) on the plate. Dose response curve for Human/Cynomolgus Activin RIIB, hFc Tag with the EC50 of 4.2ng/ml determined by ELISA (QC Test). Immobilized Human/Mouse/Rat GDF-8, No Tag at 1μg/ml (100μl/well) on the plate. Dose response curve for Human/Cynomolgus Activin RIIB, hFc Tag with the EC50 of 0.5ng/ml determined by ELISA. Human/Cynomolgus Activin RIIB, hFc Tag captured on CM5 Chip via Protein A can bind Human GDF-2, No Tag with an affinity constant of 26.57 pM as determined in SPR assay (Biacore T200).
产品描述	ACVR2B Protein, Human/Cynomolgus, Recombinant (hFc) is expressed in HEK293 Cells. The accession number is Q13705-1(Human)/XP_045242398.1(Cynomolgus).
种属	Human,Cynomolgus
表达系统	HEK293 Cells
标签	C-hFc
蛋白编号	Q13705-1(Human)/XP_045242398.1(Cynomolgus)
别名	activin A receptor, type IIB
蛋白构建	Ser19-Thr137 (Human)/Ser40-Thr158 (Cynomolgus)
蛋白纯度	> 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC
分子量	39.6 kDa (Predicted); 55-70 kDa (Reducing conditions due to glycosylation)
内毒素	< 1.0 EU/μg of the protein as determined by the LAL method.
蛋白性状	Lyophilized powder
缓冲液	Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
复溶方法	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice.
研究背景	ActRIIB (activin receptor type-2B) is an activin receptor subtype constitutively expressed in the whole body, playing a role in cellular proliferation, differentiation, and metabolism. For its various physiological activities, ActRIIB interacts with activin and multiple other ligands including myostatin (MSTN), growth differentiation factor 11 (GDF11), and bone morphogenetic protein 9 (BMP9).