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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-SWAP70 Polyclonal Antibody

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货号 TMAB-13296

Anti-SWAP70 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 SWAP70。Anti-SWAP70 Polyclonal Antibody 可用于 WB。

Anti-SWAP70 Polyclonal Antibody

Anti-SWAP70 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-13296

Anti-SWAP70 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 SWAP70。Anti-SWAP70 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-SWAP70 Polyclonal Antibody is a Rabbit antibody targeting SWAP70. Anti-SWAP70 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Cell membrane. Nucleus. Cell projection > lamellipodium. In resting B-cells it is localized mainly in the cytoplasm and upon cell activation it is recruited to the plasma membrane and then translocates to the nucleus. In activated, class-switching B-cells it is associated with membrane IgG but not IgM. Localized to loose actin filament arrays located behind actively extending lamellipodia.
组织特异性Expressed only in mature B-cells including those associated with mucosa-associated tissue and bronchus-associated tissue (PubMed:10681448). Widely expressed. Abundant in spleen, and fairly abundant in kidney, lung and liver. Also found in monocytes and macrophages (PubMed:12925760).
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
抗原信息
免疫原
KLH conjugated synthetic peptide: human SWAP70
抗原种属
Human
基因名称
SWAP70
基因ID
23075
蛋白名称
Switch-associated protein 70
Uniprot ID
Q9UH65
功能
Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC. It also mediates signaling of membrane ruffling. Regulates the actin cytoskeleton as an effector or adapter protein in response to agonist stimulated phosphatidylinositol (3,4)-bisphosphate production and cell protrusion.
化学信息
分子量Theoretical: 69 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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