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Anti-Legumain Polyclonal Antibody

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货号 TMAB-08270

Anti-Legumain Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Legumain。Anti-Legumain Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF,FCM。

Anti-Legumain Polyclonal Antibody

Anti-Legumain Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-08270

Anti-Legumain Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Legumain。Anti-Legumain Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF,FCM。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍


生物活性
产品描述
Anti-Legumain Polyclonal Antibody is a Rabbit antibody targeting Legumain. Anti-Legumain Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF,FCM.
Ig Type
IgG
反应种属
Human,Mouse (predicted:Rat,Dog,Cow,Horse)
应用WBIHC-PIHC-FrIFFCM
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; FCM: 3μg/Test
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Lysosome (By similarity).
组织特异性Ubiquitous. Particularly abundant in kidney, heart and placenta.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene encodes a cysteine protease that has a strict specificity for hydrolysis of asparaginyl bonds. This enzyme may be involved in the processing of bacterial peptides and endogenous proteins for MHC class II presentation in the lysosomal/endosomal systems. Enzyme activation is triggered by acidic pH and appears to be autocatalytic. Protein expression occurs after monocytes differentiate into dendritic cells. A fully mature, active enzyme is produced following lipopolysaccharide expression in mature dendritic cells. Overexpression of this gene may be associated with the majority of solid tumor types. This gene has a pseudogene on chromosome 13. Several alternatively spliced transcript variants have been described, but the biological validity of only two has been determined. These two variants encode the same isoform. [provided by RefSeq, Jul 2008].
抗原信息
免疫原
KLH conjugated synthetic peptide: human Legumain
抗原种属
Human
基因名称
LGMN
基因ID
蛋白名称
Legumain
Uniprot ID
功能
Has a strict specificity for hydrolysis of asparaginyl bonds. Can also cleave aspartyl bonds slowly, especially under acidic conditions. May be involved in the processing of proteins for MHC class II antigen presentation in the lysosomal/endosomal system.
化学信息
分子量Theoretical: 46 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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