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Anti-MUSK Monoclonal Antibody (7C469) 是一种 Mouse 抗体,靶向 MUSK。Anti-MUSK Monoclonal Antibody (7C469) 可用于 IHC,IF。
别名 FADS, CMS9
Anti-MUSK Monoclonal Antibody (7C469) 是一种 Mouse 抗体,靶向 MUSK。Anti-MUSK Monoclonal Antibody (7C469) 可用于 IHC,IF。

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| 产品描述 | Anti-MUSK Monoclonal Antibody (7C469) is a Mouse antibody targeting MUSK. Anti-MUSK Monoclonal Antibody (7C469) can be used in IHC,IF. |
| 别名 | FADS, CMS9 |
| Ig Type | IgG1 |
| 克隆号 | 7C469 |
| 反应种属 | Human |
| 应用 | IHCIF |
| 推荐剂量 | IHC: 1/200-1/1000; IF: 1/200-1/1000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | Hybridoma Monoclonal Antibody |
| 纯化方式 | Purified by protein A or protein G |
| 性状 | Liquid |
| 缓冲液 | PBS with 0.05% sodium azide |
| 浓度 | 1 mg/ml |
| 研究背景 | MuSK (for Muscle Specific Kinase) is a receptor tyrosine kinase required for the formation of the neuromuscular junction (NMJ). It induces cellular signaling by causing the addition of phosphate molecules to particular tyrosines on itself, and on proteins which bind the cytoplasmic domain of the receptor. It is activated by a nerve-derived proteoglycan called agrin. During development, the growing end of motor neuron axons secrete a protein called agrin.This protein binds to several receptors on the surface of skeletal muscle. The receptor which seems to be required for formation of the neuromuscular junction (NMJ), which comprises the nerve-muscle synapse is called MuSK. MUSK mutations lead to decreased agrin-dependent AchR aggregation, a critical step in the formation of the neuromuscular junction. |
| 偶联 | Unconjugated |
| 免疫原 | Purified recombinant extracellular fragment of human MUSK (aa24-209) fused with hIgGFc tag expressed in HEK293 cell line. |
| 抗原种属 | Human |
| 基因名称 | MUSK |
| 基因ID | |
| 蛋白名称 | Muscle, skeletal receptor tyrosine-protein kinase |
| Uniprot ID |
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |