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Anti-MUSK Monoclonal Antibody (7C469)

Synonyms: FADS, CMS9
货号 TMAT-0554 一键复制产品信息
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Anti-MUSK Monoclonal Antibody (7C469) 是一种 Mouse 抗体,靶向 MUSK。Anti-MUSK Monoclonal Antibody (7C469) 可用于 IHC,IF。

Anti-MUSK Monoclonal Antibody (7C469)

一键复制产品信息
Rating icon 还可以
货号 TMAT-0554

别名 FADS, CMS9

Anti-MUSK Monoclonal Antibody (7C469) 是一种 Mouse 抗体,靶向 MUSK。Anti-MUSK Monoclonal Antibody (7C469) 可用于 IHC,IF。

Anti-MUSK Monoclonal Antibody (7C469)
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产品介绍


生物活性
产品描述
Anti-MUSK Monoclonal Antibody (7C469) is a Mouse antibody targeting MUSK. Anti-MUSK Monoclonal Antibody (7C469) can be used in IHC,IF.
别名
FADS, CMS9
Ig Type
IgG1
克隆号
7C469
反应种属
Human
应用IHCIF
推荐剂量
IHC: 1/200-1/1000; IF: 1/200-1/1000
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式Purified by protein A or protein G
性状Liquid
缓冲液PBS with 0.05% sodium azide
浓度1 mg/ml
研究背景MuSK (for Muscle Specific Kinase) is a receptor tyrosine kinase required for the formation of the neuromuscular junction (NMJ). It induces cellular signaling by causing the addition of phosphate molecules to particular tyrosines on itself, and on proteins which bind the cytoplasmic domain of the receptor. It is activated by a nerve-derived proteoglycan called agrin. During development, the growing end of motor neuron axons secrete a protein called agrin.This protein binds to several receptors on the surface of skeletal muscle. The receptor which seems to be required for formation of the neuromuscular junction (NMJ), which comprises the nerve-muscle synapse is called MuSK. MUSK mutations lead to decreased agrin-dependent AchR aggregation, a critical step in the formation of the neuromuscular junction.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Purified recombinant extracellular fragment of human MUSK (aa24-209) fused with hIgGFc tag expressed in HEK293 cell line.
抗原种属
Human
基因名称
MUSK
基因ID
蛋白名称
Muscle, skeletal receptor tyrosine-protein kinase
Uniprot ID
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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