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别名 Bavencio
Anti-Avelumab Antibody (9X18) 是一种 Mouse 抗体,靶向 Avelumab。Anti-Avelumab Antibody (9X18) 可用于 ELISA, Competitive ELISA。
Anti-Avelumab Antibody (9X18) 是一种 Mouse 抗体,靶向 Avelumab。Anti-Avelumab Antibody (9X18) 可用于 ELISA, Competitive ELISA。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 40 μg | ¥ 1,609 | 5日内发货 |
| 产品描述 | Anti-Avelumab Antibody (9X18) is a Mouse antibody targeting Avelumab. Anti-Avelumab Antibody (9X18) can be used in ELISA, Competitive ELISA. |
| 别名 | Bavencio |
| Ig Type | IgG1,κ |
| 克隆号 | 9X18 |
| 特异性 | Avelumab |
| 应用 | ELISACompetitive ELISA |
| 推荐剂量 | ELISA: 0.001-0.1 µg/ml; Competitive ELISA: 10-50 µg/ml |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 纯化方式 | Protein A affinity column |
| 性状 | Lyophilized. Reconstitute the lyophilized powder with deionized water (or equivalent) to a final concentration of 0.5 mg/ml. |
| 缓冲液 | Lyophilized with PBS, pH 7.2, containing 0.02% sodium azide. |
| 研究背景 | Avelumab with trade name Bavencio, is an FDA-approved drug to treat Merkel cell carcinoma, urothelial carcinoma, and renal cell carcinoma. Avelumab is a whole monoclonal antibody of isotype IgG1 that binds to the programmed death-ligand 1 (PD-L1) and therefore inhibits binding to its receptor programmed cell death 1 (PD-1). PD-L1 can be highly expressed on certain tumors, which is thought to lead to reduced activation of immune cells (cytotoxic T-cells in particular) that might otherwise recognize and attack the cancer. Inhibition of PD-L1 by Avelumab can remove this inhibitor effect and thereby engender an anti-tumor response. It is one of several ways to block inhibitory signals related to T-cell activation, a more general strategy known as "immune checkpoint inhibition." |
| 偶联 | Unconjugated |
| 免疫原 | Avelumab |
| 储存方式 | The lyophilized product store at -20°C or -80°C for 12 months. The reconstituted antibody can be stored at 2°C-8°C for 2-3 weeks or at -20°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | -20°C for 1 year |