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Anti-Phospho-CREB1 (Ser133) Polyclonal Antibody 2

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Anti-Phospho-CREB1 (Ser133) Polyclonal Antibody 2
产品编号 TMAC-00966
别名 p-CREB1 (Ser133), p-CREB1 (S133), CREB1 (p-Ser133), CREB1 (p-S133)

Anti-Phospho-CREB1 (Ser133) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-CREB1 (Ser133)。Anti-Phospho-CREB1 (Ser133) Polyclonal Antibody 可用于 WB,IHC。

Anti-Phospho-CREB1 (Ser133) Polyclonal Antibody 2

Anti-Phospho-CREB1 (Ser133) Polyclonal Antibody 2

Rating icon 还可以
Anti-Phospho-CREB1 (Ser133) Polyclonal Antibody 2
产品编号 TMAC-00966 别名 p-CREB1 (Ser133), p-CREB1 (S133), CREB1 (p-Ser133), CREB1 (p-S133)

Anti-Phospho-CREB1 (Ser133) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-CREB1 (Ser133)。Anti-Phospho-CREB1 (Ser133) Polyclonal Antibody 可用于 WB,IHC。

规格价格库存数量
50 μL
¥ 1,495
5日内发货
100 μL
¥ 2,235
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-CREB1 (Ser133) Polyclonal Antibody is a Rabbit antibody targeting Phospho-CREB1 (Ser133). Anti-Phospho-CREB1 (Ser133) Polyclonal Antibody can be used in WB,IHC.
别名p-CREB1 (Ser133), p-CREB1 (S133), CREB1 (p-Ser133), CREB1 (p-S133)
Ig Type
IgG
交叉反应
Human,Mouse,Rat
验证活性
1. Western blot analysis of extracts from Hela cells untreated or treated with UV using CREB (Phospho-Ser133) Antibody TMAC-00966.
2. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using CREB (Phospho-Ser133) Antibody TMAC-00966 (left) or the same antibody preincubated with blocking peptide (right).
应用
抗体种类
Polyclonal
宿主来源Rabbit
构建方式Polyclonal Antibody
纯化方式Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
性状Liquid
缓冲液Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
研究背景CREB1 is a transcription factor that is a member of the bZIP family of DNA binding proteins. It binds as a homodimer to the CRE (cAMP-Responsive Element), an octameric palindrome containing a conserved core sequence, 5-prime-TGACG-3-prime. It consists of two transcript variants encoding respective isoforms produced by alternate splicing. It is mapped to 2q32.3-q34 . It is phosphorylated by several protein kinases and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. CREB1 is crucial for the consolidation of long-term conditioned fear memories, but not for encoding, storage, or retrieval of these memories. It is required for the stability of reactivated or retrieved conditioned fear memories .
偶联与修饰
偶联
Unconjugated
其他可选修饰符
Phospho
抗原信息
免疫原
Peptide sequence around phosphorylation site of serine 133 (R-P-S(p)-Y-R) derived from Human CREB
抗原种属
human
Uniprot ID
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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