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顶部生物活性储存和溶解信息计算器

Anti-PCAF Antibody (2Q586)

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Anti-PCAF Antibody (2Q586)
产品编号 TMAC-03094
别名 Pcaf, P300/CBP-associated factor, p300/CBP associated factor, P/CAF, P, Lysine acetyltransferase 2B, KAT2B_HUMAN, KAT2B, K(lysine) acetyltransferase 2B, Histone acetyltransferase PCAF, Histone acetyltransferase KAT2B, Histone acetylase PCAF, GCN5L1, GCN5L, GCN5, CREBBP associated factor, CAF

Anti-PCAF Antibody (2Q586) 是一种 Rabbit 抗体，靶向 PCAF。Anti-PCAF Antibody (2Q586) 可用于 WB,IP,FCM。

Anti-PCAF Antibody (2Q586)

Anti-PCAF Antibody (2Q586)

Rating icon 还可以
Anti-PCAF Antibody (2Q586)
产品编号 TMAC-03094 别名 Pcaf, P300/CBP-associated factor, p300/CBP associated factor, P/CAF, P, Lysine acetyltransferase 2B, KAT2B_HUMAN, KAT2B, K(lysine) acetyltransferase 2B, Histone acetyltransferase PCAF, Histone acetyltransferase KAT2B, Histone acetylase PCAF, GCN5L1, GCN5L, GCN5, CREBBP associated factor, CAF

Anti-PCAF Antibody (2Q586) 是一种 Rabbit 抗体，靶向 PCAF。Anti-PCAF Antibody (2Q586) 可用于 WB,IP,FCM。

规格价格库存数量
50 μL
¥ 1,495
5日内发货
100 μL
¥ 2,495
5日内发货
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产品介绍

生物活性
产品描述
Anti-PCAF Antibody (2Q586) is a Rabbit antibody targeting PCAF. Anti-PCAF Antibody (2Q586) can be used in WB,IP,FCM.
别名Pcaf, P300/CBP-associated factor, p300/CBP associated factor, P/CAF, P, Lysine acetyltransferase 2B, KAT2B_HUMAN, KAT2B, K(lysine) acetyltransferase 2B, Histone acetyltransferase PCAF, Histone acetyltransferase KAT2B, Histone acetylase PCAF, GCN5L1, GCN5L, GCN5, CREBBP associated factor, CAF
Ig Type
IgG
交叉反应
Human,Mouse,Rat
验证活性
1. Western blot analysis of PCAF on rat kidney tissue (1) and K562 cell (2) lysate using anti-PCAF antibody at 1/500 dilution.
2. Flow cytometric analysis of Hela cells with PCAF antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.
应用
WB
IP
FCM
推荐剂量
WB: 1:500-2000; IP: 1:10-50; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景In the intact cell, DNA closely associates with histones and other nuclear proteins to form chromatin. The remodeling of chromatin is believed to be a critical component of transcriptional regulation and a major source of this remodeling is brought about by the acetylation of nucleosomal histones. Acetylation of lysine residues in the amino terminal tail domain of histone results in an allosteric change in the nucleosomal conformation and an increased accessiblity to transcription factors by DNA. Conversely, the deacetylation of histones is associated with transcriptional silencing. Several mammalian proteins have been identified as nuclear histone acetylases, including GCN5, PCAF (for p300/CBP-associated factor), p300/CBP and the TFIID subunit TAF II p250. Mammalian HDAC1 (also designated HD1) and HDAC2 (also designated mammalian RPD3), both of which are related to the yeast transcriptional regulator Rpd3p, have been identified as histone deacetylases.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
Q92831
化学信息
分子量Theoretical: 93 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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