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Anti-Phospho-Gli1 (Ser112/Thr115/Ser116) Polyclonal Antibody
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还可以货号 TMAB-10739
Anti-Phospho-Gli1 (Ser112/Thr115/Ser116) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-Gli1 (Ser112/Thr115/Ser116)。Anti-Phospho-Gli1 (Ser112/Thr115/Ser116) Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。
Anti-Phospho-Gli1 (Ser112/Thr115/Ser116) Polyclonal Antibody
Anti-Phospho-Gli1 (Ser112/Thr115/Ser116) Polyclonal Antibody
一键复制产品信息 还可以货号 TMAB-10739
Anti-Phospho-Gli1 (Ser112/Thr115/Ser116) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-Gli1 (Ser112/Thr115/Ser116)。Anti-Phospho-Gli1 (Ser112/Thr115/Ser116) Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,165 | 5日内发货 | |
| 100 μL | ¥ 1,970 | 5日内发货 | |
| 200 μL | ¥ 2,795 | 5日内发货 |
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| 产品描述 | Anti-Phospho-Gli1 (Ser112/Thr115/Ser116) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Gli1 (Ser112/Thr115/Ser116). Anti-Phospho-Gli1 (Ser112/Thr115/Ser116) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| 反应种属 | Mouse (predicted:Human,Rat,Rabbit) |
| 应用 | IHC-PIHC-FrIF |
| 推荐剂量 | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cytoplasm. Nucleus. Tethered in the cytoplasm by binding to SUFU. Activation and translocation to the nucleus is promoted by interaction with STK36. Phosphorylation by ULK3 may promote nuclear localization. Translocation to the nucleus is promoted by interaction with ZIC1. |
| 组织特异性 | Testis, myometrium and fallopian tube. Also expressed in the brain with highest expression in the cerebellum, optic nerve and olfactory tract. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | This gene encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009] |
| 免疫原 | KLH conjugated Synthesised phosphopeptide: human Gli1 around the phosphorylation site of S112/ T115/ S116 |
| 抗原种属 | Human |
| 基因名称 | GLI1 |
| 基因ID | |
| 蛋白名称 | Zinc finger protein GLI1 |
| Uniprot ID | |
| 功能 | Acts as a transcriptional activator. May regulate the transcription of specific genes during normal development. May play a role in craniofacial development and digital development, as well as development of the central nervous system and gastrointestinal tract. Mediates SHH signaling and thus cell proliferation and differentiation. |
| 分子量 | Theoretical: 118 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |
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